In order to compile a list of all the backlinks for a given webpage, we need knowledge about all the outgoing links on the web. Traversing the web and storing all the backlink data in a database allows us to efficiently retrieve the list of backlinks for a web page on demand. However, the web consists of billions of backlinks which translates to terabytes of data. As the web is continuously evolving, ...

This study discusses and estimates the backward-bending supply curve, using data for three years over a six-year time span from the inshore purse seine fishery in Khanh Hoa province, Vietnam. Four different models are developed for estimation based on fisheries data, in the absence of stock survey data. The estimated maximum sustainable yield for the anchovy in south-central Vietnam ranges from ...

An investigation was conducted to identify the allochthonous microbiota (entire intestine) and the autochthonous microbiota in proximal intestine (PI) and distal intestine (DI) of four species of Indian air-breathing fish (climbing perch; Anabas testudineus, murrel; Channa punctatus, walking catfish; Clarias batrachus and stinging catfish; Heteropneustes fossilis) by PCR based denaturing gradient ...

Bacteria carry antibiotic resistant genes on movable sections of DNA that allow them to select the relevant genes on demand.

One way to mitigate the ongoing antimicrobial resistance crisis is to discover and develop new classes of antibiotics. As all antibiotics at some point need to either cross or just interact with the bacterial membrane, there is a need for representative models of bacterial membranes and efficient methods to characterize the interactions with novel molecules -both to generate new knowledge and to ...

Genomic epidemiology is a tool for tracing transmission of pathogens based on whole-genome sequencing. We introduce the mGEMS pipeline for genomic epidemiology with plate sweeps representing mixed samples of a target pathogen, opening the possibility to sequence all colonies on selective plates with a single DNA extraction and sequencing step. The pipeline includes the novel mGEMS read binner for ...

Abstract Background The main cause of pulpal and periradicular pathosis are microorganisms and their by products in the root canal system. These have to be eliminated to promote healing. Because it´s impossible to achieve a bacteria-free root canal an additional goal of endodontic therapy is to seal the root canal system from the outside environment. Today the standard method for filling the ...

Methicillin-resistant Staphylococcus aureus (MRSA) has evolved numerous antimicrobial resistance mechanisms and is identified as a serious public health threat by the World Health Organization and U.S. Centers for Disease Control and Prevention. The glycopeptide vancomycin (VAN) remains a cornerstone of therapy for severe MRSA infections despite increasing reports of therapeutic failure in hospitalized ...

The problem of antibiotic resistance has become a challenge for our public health and society; it has allowed infectious diseases to re-emerge as a risk to human health. New antibiotics that are introduced to the market face the rise of resistant pathogens after a certain period of use. The relatively fast development of resistance against some antibiotics seems to be closely linked to their microbial ...

Bacteriocins are ribosomally-synthesized antimicrobial peptides, showing great potential as novel treatment options for multidrug-resistant pathogens. In this study, we designed a novel hybrid bacteriocin, Hybrid 1 (H1), by combing the N-terminal part and the C-terminal part of the related bacteriocins enterocin K1 (K1) and enterocin EJ97 (EJ97), respectively. Like the parental bacteriocins, H1 used ...