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    • T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF 

      Abraityte, Aurelija; Aukrust, Pål; Kou, Lei; Anand, Inder S.; Young, James; Mcmurray, John J.V.; van Veldhuisen, Dirk J.; Gullestad, Lars; Ueland, Thor (Journal article; Tidsskriftartikkel, 2018-07-26)
      <i>Background</i>: Activated leukocytes may contribute to the development and progression of heart failure (HF). We investigated the predictive value of circulating levels of stable and readily detectable markers reflecting both monocyte/macrophage and T-cell activity, on clinical outcomes in HF patients with reduced ejection fraction (HFrEF).<p> <p><i>Methods</i>: The association between ...

    • T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases 

      Høye, Eirik; Dagenborg, Vegar Johansen; Kristensen, Annette Torgunrud; Lund-Andersen, Christin; Fretland, Åsmund Avdem; Lorenz, Susanne; Edwin, Bjørn von Gohren; Hovig, Eivind; Fromm, Bastian; Inderberg, Else Marit; Greiff, Victor; Ree, Anne Hansen; Flatmark, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-10)
      Background - Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC has been disappointing. Administration of cytotoxic chemotherapy may cause increased density of tumor-infiltrating T cells, which has been associated with improved response to ICI. This study aimed to quantify and ...

    • T cell therapy after allogeneic stem cell transplantation : titration of IL-2 concentration when expanding cord blood t lymphocytes with and without IL-7, in order to optimize expansion protocol for donor lymphocyte infusion 

      Rydsaa, Lars Jakob Hope (Master thesis; Mastergradsoppgave, 2011-09)
      Umbilical cord blood (UCB) is a promising, increasingly used option for allogeneic stem cell transplantation. Among the beneficial features are availability, permissiveness regarding human leukocyte antigen (HLA)-matching, and low incidences of graft-versus-host disease (GVHD). A great disadvantage is the low cell number in the grafts and therefore insufficient T cell numbers to prepare for donor ...

    • T-box transcription factor eomesodermin/Tbr2 in Atlantic cod (Gadus morhua L.): Molecular characterization, promoter structure and function analysis 

      Chi, Heng; Sørmo, Kristian Gillebo; Diao, Jing; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      Eomesodermin (Eomes) is a member of T-box transcription factor family and plays an important role in the regulation of a wide variety of developmental processes and immune response in animals. Here we report cloning and characterization of the full-length cDNA of Atlantic cod Eomes (GmEomes), which possesses a TBOX_3 domain similar to its counterpart in mammals. The regulated expression was observed ...

    • T90 Codends Improve the Size Selectivity and Catch Efficiency of Shrimp Trawl Fisheries for Southern Velvet Shrimp (Metapenaeopsis palmensis) in the South China Sea 

      Yang, Bingzhong; Herrmann, Bent (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-26)
      In order to obtain gear-based management instruments of shrimp trawl fishery for southern velvet shrimp in the South China Sea (SCS), the size selectivity and catch efficiency of four codends were tested and compared. These codends included two mesh sizes, 30 and 35 mm, and two mesh shapes, T0 (diamond-mesh) and T90 (diamond-mesh turned by 90°), respectively. Our results demonstrated that increasing ...

    • TA 2020/25 Krigsmonumentet i kirkeparken i Tromsø. Flytting av minnestøtte i Kirkeparken, Tromsø kommune 

      Hesjedal, Anders; Jørgensen, Erlend Kirkeng (Research report; Forskningsrapport, 2022-02-10)
      I forbindelse med flytting av krigsmonumentet i Kirkeparken i Tromsø ble det foretatt graving under arkeologisk overvåkning. Det ble gravd et rektangulært område 5,4mx4,6mx0,8m til fundamentet for monumentet. Det ble avdekket spor etter tidlig 1900-tall aktivitet, men ingen automatisk fredede kulturminner.

    • «Ta deg bryet med å lete etter veien inn». En studie av hvordan lærere arbeider med å etablere relasjoner til elever med problemadferd. 

      Aspen, Sara Louise (Master thesis; Mastergradsoppgave, 2019-05-14)
      Denne studien undersøker hvordan lærere arbeider med å etablere relasjoner til elever med problemadferd. Relasjonskompetanse er et sentralt begrep i skolen, og jeg anser en lærers relasjonskompetanse som svært viktig, på samme måte som den faglige. Jeg ble motivert til å fordype meg i temaet etter en praksisperiode. I praksisperioden observerte jeg utfordringer i relasjonen mellom lærere og en elev ...

    • Tablet as a digital tool in supervision of student teachers’ practical training 

      Mathisen, Petter; Bjørndal, Cato R. P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      In the project “Tablets in Practicum Supervision”, the tablet has been tested as a tool for observation and supervision in Norwegian teacher education. The study incorporates 14 practicum supervision groups and focuses on how the use of tablets can influence the quality of the supervision and the coherence between teaching, observation and supervision. Throughout the supervision process, the ...

    • "Tack för musiken". Ett porträtt av musikprofessor Göte Strandsjö och hans samtid i ord, bild och toner 

      Eriksson, Anitha (Research report; Forskningsrapport, 2008)

    • Tackling Gender Inequality In Doctoral Supervision - An Intersectional Toolkit Involving Hearts, Minds, Policies, And Practices 

      Wisker, Gina; Fossland, Trine Medby (Journal article; Tidsskriftartikkel, 2023-11-01)
      Doctoral supervision is both a rewarding and challenging experience for supervisors and doctoral students, while effective supervision and research practice is of crucial importance for the developmental process and both students' and supervisors' careers. Although several challenges in the research journey are strictly research-focused, supervision is a human activity where intersectional aspects ...

    • Tafatt og «tatlete» fra granskingsutvalget 

      Frantsvåg, Jan Erik (Journal article; Tidsskriftartikkel, 2017-05-08)
      At man unnlater å felle forskeren for uredelighet fordi vedkommende velger å ikke forklare seg, åpner for at andre som granskes kan slippe unna på samme måte. Og så snillistisk bør man ikke være, mener Jan Erik Frantsvåg ved UiT.

    • Tags and Negative Polarity Items 

      Østbø Munch, Christine B.; Garbacz, Piotr (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-22)
      Tags are elements or (remnant) clauses that attach to a sentence in order to signal various speech acts, e.g. the common question tags of the type is it? isn’t it?. An affirmative tag, which is used in order for the speaker to confirm the content of the matrix clause is presented in (1). (1) Pappa kan hämta dig vid stationen, kan han nog (#1435) (Swedish) dad can fetch you with station.DEF can ...

    • Tailored anti-biofilm activity – Liposomal delivery for mimic of small antimicrobial peptide 

      Hemmingsen, Lisa Myrseth; Giordani, Barbara; Paulsen, Marianne Hagensen; Vanic, Zeljka; Flaten, Gøril Eide; Vitali, Beatrice; Basnet, Purusotam; Bayer, Annette; Strøm, Morten B.; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)
      The eradication of bacteria embedded in biofilms is among the most challenging obstacles in the management of chronic wounds. These biofilms are found in most chronic wounds; moreover, the biofilm-embedded bacteria are considerably less susceptible to conventional antimicrobial treatment than the planktonic bacteria. Antimicrobial peptides and their mimics are considered attractive candidates in the ...

    • Tailored Iterated Greedy metaheuristic for a scheduling problem in metal 3D printing 

      Ying, Kuo-Ching; Pourhejazy, Pourya; Huang, Ya-Hsuan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-24)
      This article contributes to the additive manufacturing-based production planning literature by developing a Mixed-Integer Linear Programming (MILP) formulation for the Identical Parallel 3D-Printing Machines Scheduling Problem considering batching, multiple build platforms of restricted sizes, and sequence-independent setup times. Besides, a customized metaheuristic, named the Tailored Iterated ...

    • Tailored Leaching Tests as a Tool for Environmental Management of Mine Tailings Disposal at Sea 

      Pedersen, Kristine B.; Lejon, Tore; Evenset, Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-10)
      The expanding human activities in coastal areas increase the need for developing solutions to limit impacts on the marine environment. Sea disposal affects the marine environment, but despite the growing knowledge of potential impacts, there are still no standardized leaching tests for sea disposal. The aim of this study was to contribute to the development of leaching tests, exemplified using ...

    • Tailoring ties: Leadership in the spaces between — When safety and efficiency are essential 

      Vederhus, Lillian (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)

    • TAK1 converts Sequestosome 1/p62 from an autophagy receptor to a signaling platform 

      Kehl, Stephanie R; Soos, Brandy-Lee A; Saha, Bhaskar; Choi, Seong Won; Herren, Anthony W; Johansen, Terje; Mandell, Michael A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-25)
      The protein p62/Sequestosome 1 (p62) has been described as a selective autophagy receptor and independently as a platform for pro‐inflammatory and other intracellular signaling. How these seemingly disparate functional roles of p62 are coordinated has not been resolved. Here, we show that TAK1, a kinase involved in immune signaling, negatively regulates p62 action in autophagy. TAK1 reduces p62 ...

    • Take control of your PhD journey! Erfaringer fra et skreddersydd undervisningsopplegg 

      Andreassen, Helene N.; Aspaas, Per Pippin (Conference object; Konferansebidrag, 2015-11-03)
      Universitetsbiblioteket ved UiT Norges arktiske universitet avholdt våren 2015 en seminarrekke for PhD-studenter, «Take control of your PhD journey: From (p)reflection to publishing». Seminaret besto av fire deler: 1) akademisk integritet, plagiat og forskningens samfunnsrolle; 2) litteratursøk i databaser for ulike fagdisipliner; 3) referansehåndteringsverktøyet EndNote; 4) publisering, særlig Open ...

    • Take control of your PhD journey: A librarian's perspective 

      Andreassen, Helene N.; Østvand, Lene (Conference object; Konferansebidrag, 2017-04-10)
      PhD students as a library user group are receiving increased focus in the development of library services. In addition to write their doctoral thesis, they need to balance the roles as “good academics" and “good scientists”, and a key element in this respect is raised awareness around academic integrity and publication channels. In this breakout session, based on experiences from our own teaching ...

    • Take-Home Exams in University Mathematics and Science Subjects: Some Ethical Considerations 

      Rensaa, Ragnhild Johanne; Kristiansen, Raymond (Journal article; Tidsskriftartikkel; Peer reviewed, 2024)
      This article addresses some challenging perspectives related to offering take-home exams in mathematics at university level. The challenges arose during work on a previous article where four perspectives originating from Bjerrum Nielsen’s framework (2003) were used to analyze universities’ assessment methods during the Covid lockdown in our country. The perspectives had some ethical considerations ...