Seredkina, Natalya; van der Vlag, Johan; Berden, Jo; Mortensen, Elin Synnøve; Rekvig, Ole Petter (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Autoantibodies to components of chromatin, which include double-stranded DNA (dsDNA), histones and nucleosomes, are central
in the pathogenesis of lupus nephritis. How anti-chromatin autoantibodies exert their nephritogenic activity, however, is controversial.
One model assumes that autoantibodies initiate inflammation when they cross-react with intrinsic glomerular structures such
as components ...