Blar i forfatter "Masala, Giovanna"

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    • Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition 

      Kliemann, Nathalie; Viallon, Vivian; Murphy, Neil; Beeken, Rebecca J.; Rothwell, Joseph A.; Rinaldi, Sabina; Assi, Nada; van Roekel, Eline H.; Schmidt, Julie A.; Borch, Kristin Benjaminsen; Agnoli, Claudia; Rosendahl, Ann H.; Sartor, Hanna; Huerta, José María; Tjønneland, Anne; Halkjær, Jytte; Bueno-de-Mesquita, Bas; Gicquiau, Audrey; Achaintre, David; Aleksandrova, Krasimira; Schulze, Matthias B.; Heath, Alicia K.; Tsilidis, Konstantinos K.; Masala, Giovanna; Panico, Salvatore; Kaaks, Rudolf; Fortner, Renée T.; Van Guelpen, Bethany; Dossus, Laure; Scalbert, Augustin; Keun, Hector C.; Travis, Ruth C.; Jenab, Mazda; Johansson, Mattias; Ferrari, Pietro; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-30)
      Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study.<p> <p>Methods: Targeted mass spectrometry ...

    • A metabolomic study of red and processed meat intake and acylcarnitine concentrations in human urine and blood 

      Wedekind, Roland; Kiss, Agneta; Keski-Rahkonen, Pekka; Viallon, Vivian; Rothwell, Joseph A; Cross, Amanda J.; Rostgaard-Hansen, Agnetha Linn; Sandanger, Torkjel M; Jakszyn, Paula; Schmidt, Julie A; Pala, Valeria; Vermeulen, Roel; Schulze, Matthias B; Kühn, Tilman; Johnson, Theron; Trichopoulou, Antonia; Peppa, Eleni; La Vechia, Carlo; Masala, Giovanna; Tumino, Rosario; Sacerdote, Carlotta; Wittenbecher, Clemens; de Magistris, Maria Santucci; Dahm, Christina C; Severi, Gianluca; Romana Mancini, Francesca; Vainio, Elisabete Weiderpass; Gunter, Marc J.R.; Huybrechts, Inge; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-03)
      <p>Background - Acylcarnitines (ACs) play a major role in fatty acid metabolism and are potential markers of metabolic dysfunction with higher blood concentrations reported in obese and diabetic individuals. Diet, and in particular red and processed meat intake, has been shown to influence AC concentrations but data on the effect of meat consumption on AC concentrations is limited. <p>Objectives - ...

    • A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Cross, Amanda J; Abubakar, Mustapha; Jenab, Mazda; Aleksandrova, Krasmira; Boutron-Ruault, Marie-Christine; Dossus, Laure; Racine, Antoine; Kühn, Tilman; Katzke, Verena A.; Tjønneland, Anne; Petersen, Kristina E N; Overvad, Kim; Quiros, J Ramon; Jakszyn, Paula; Molina-Montes, Esther; Dorronsoro, Miren; Huerta, José-Maria; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nick; Travis, Ruth C; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Siersema, Peter D; Peeters, Petra H; Ohlsson, Bodil; Ericson, Ulrika; Palmqvist, Richard; Nyström, Hanna; Weiderpass, Elisabete; Skeie, Guri; Freisling, Heinz; Kong, So Yeon; Tsilidis, Kostas; Muller, David C; Riboli, Eilo; Gunter, Marc J (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-05)
      Background:<br> Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterparts. ...

    • Novel Biomarkers of Habitual Alcohol Intake and Associations With Risk of Pancreatic and Liver Cancers and Liver Disease Mortality 

      Loftfield, Erikka; Stepien, Magdalena; Viallon, Vivian; Trijsburg, Laura; Rothwell, Joseph A.; Robinot, Nivonirina; Biessy, Carine; Bergdahl, Ingvar A.; Bodén, Stina; Schulze, Matthias B.; Bergman, Manuela; Weiderpass, Elisabete; Schmidt, Julie A.; Zamora-Ros, Raúl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Sonestedt, Emily; Ohlsson, Bodil; Katzke, Verena; Kaaks, Rudolf; Ricceri, Fulvio; Tjønneland, Anne; Dahm, Christina C.; Sánchez, Maria-Jose; Trichopoulou, Antonia; Tumino, Rosario; Chirlaque, María-Dolores; Masala, Giovanna; Ardanaz, Eva; Vermeulen, Roel; Brennan, P; Albanes, Demetrius; Weinstein, Stephanie J.; Scalbert, Augustin; Freedman, Neal D.; Gunter, Marc; Jenab, Mazda; Sinha, Rashmi; Keski-Rahkonen, Pekka; Ferrari, Pietro (Preprint; Manuskript, 2021-05-19)
      Background - Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed because of measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.<p> <p>Methods - Untargeted metabolomics was used to identify metabolites correlated with ...

    • Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study 

      Freisling, Heinz; Noh, Hwayoung; Slimani, Nadia; Chajès, Véronique; May, Anne M.; Peeters, Petra H; Weiderpass, Elisabete; Cross, Amanda J.; Skeie, Guri; Jenab, Mazda; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Katzke, Verena A.; Kühn, Tilman; Steffen, Annika; Boeing, Heiner; Tjønneland, Anne; Kyrø, Cecilie; Hansen, Camilla P.; Overvad, Kim; Duell, Eric J.; Redondo-Sánchez, Daniel; Amiano, Pilar; Navarro, Carmen; Barricarte, Aurelio; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Aune, Dagfinn; Ward, Heather; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Berrino, Franco; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Bueno-De-Mesquita, Hendrik Bastiaan; Ericson, Ulrika; Sonestedt, Emily; Winkvist, Anna; Braaten, Tonje; Romieu, Isabelle; Sabaté, Joan (Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-07-21)
      <p><i>Purpose</i>: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years.</p> <p><i>Methods</i>: This study includes 373,293 men and women, 25–70 years old, recruited between 1992 and 2000 from 10 European countries in the European ...

    • Nutrient-wide association study of 92 foods and nutrients and breast cancer risk 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Papadimitriou, Nikos; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Fagherazzi, Guy; Boeing, Heiner; Ferrari, Pietro; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Kuhn, Tilman; Turzanski-Fortner, Renee; Schulze, Matthias B.; Karakatsani, Anna; Thriskos, Paschalis; Thrichopoulou, Antonia; Masala, Giovanna; Contiero, Paolo; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Bas; Bakker, Marije F.; van Gils, Carla H.; Olsen, Karina Standahl; Skeie, Guri; Lasheras, Cristina; Agudo, Antonio; Rodrigues-Barranco, Miguel; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Drake, Isabel; Ericson, Ulrika; Johansson, Ingegerd; Winkvist, Anna; Key, Tim; Freisling, Heinz; His, Mathilde; Huybrechts, Inge; Christakoudi, Sofia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos K.; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      <i>Background</i> - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.<p> <p><i>Methods</i> - Using data from 272,098 women ...

    • Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study 

      Deschasaux, Mélanie; Huybrechts, Inge; Murphy, Neil; Julia, Chantal; Hercberg, Serge; Srour, Bernard; Kesse-Guyot, Emmanuelle; Latino-Martel, Paule; Biessy, Carine; Casagrande, Corinne; Jenab, Mazda; Ward, Heather; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Kyrø, Cecilie; Olsen, Anja; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Mahamat-Saleh, Yahya; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Schwingshackl, Lukas; Bamia, Christina; Peppa, Eleni; Trichopoulou, Antonia; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Hjartåker, Anette; Rylander, Charlotta; Skeie, Guri; Ramõn Quirõs, Jose; Jakszyn, Paula; Salamanca-Fernández, Elena; Huerta, José María; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Sonestedt, Emily; Huseinovic, Ena; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Ferrari, Pietro; Riboli, Elio; Gunter, Mark J.; Touvier, Mathilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-18)
      <p><i>Background - </i>Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British ...

    • Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study 

      Gallo, Valentina; Vanacore, Nicola; Bueno-de-Mesquita, H Bas; Vermeulen, Roel; Brayne, Carol; Pearce, Neil; Wark, Petra A; Ward, Heather A; Ferrari, Pietro; Jenab, Mazda; Andersen, Peter M; Wennberg, Patrik; Wareham, Nicholas; Katzke, Verena; Kaaks, Rudolf; Weiderpass, Elisabete; Peeters, Petra H; Mattiello, Amalia; Pala, Valeria; Barricante, Aurelio; Chirlaque, Maria-Dolores; Travier, Noemie; Travis, Ruth C; Sanchez, Maria-Jose; Pessah-Rasmussen, Helene; Petersson, Jesper; Tjønneland, Anne; Tumino, Rosario; Quiros, Jose Ramon; Trichopoulou, Antonia; Kyrozis, Andreas; Oikonomidou, Despoina; Masala, Giovanna; Sacerdote, Carlotta; Arriola, Larraitz; Boeing, Heiner; Vigl, Matthaeus; Claver-Chapelon, Francoise; Middleton, Lefkos; Riboli, Eilo; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-11)
      Previous case–control studies have suggested a possible increased risk of Amyotrophic Lateral Sclerosis (ALS) with physical activity (PA), but this association has never been studied in prospective cohort studies. We therefore assessed the association between PA and risk of death from ALS in the European Prospective Investigation into Cancer and Nutrition. A total of 472,100 individuals were included ...

    • Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study 

      Fortuin-de Smidt, Melony C.; Sewe, Maquins Odhiambo; Lassale, Camille; Weiderpass, Elisabete; Andersson, Jonas; Huerta, José María; Ekelund, Ulf; Aleksandrova, Krasimira; Tong, Tammy Yn; Dahm, Christina C.; Tjønneland, Anne; Kyrø, Cecilie; Steindorf, Karen; Schulze, Matthias B.; Katzke, Verena; Sacerdote, Carlotta; Agnoli, Claudia; Masala, Giovanna; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda Ma; Onland-Moret, N Charlotte; Wendel-Vos, Gc Wanda; van der Schouw, Yvonne T.; Borch, Kristin Benjaminsen; Agudo, Antonio; Petrova, Dafina; Chirlaque, María Dolores; Conchi, Moreno Iribas; Amiano, Pilar; Melander, Olle; Heath, Alicia K.; Aune, Dagfinn; Forouhi, Nita G.; Langenberg, Claudia; Brage, Soren; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam S.; Wennberg, Patrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-11)

    • Plant foods, dietary fibre and risk of ischaemic heart disease in the European prospective investigation into cancer and nutrition (EPIC) cohort 

      Perez-Cornago, Aurora; Crowe, Francesca L; Appleby, Paul N; Bradbury, Kathryn E; Wood, Angela M.; Jakobsen, Marianne Uhre; Johnson, Laura; Sacerdote, Carlotta; Steur, Marinka; Weiderpass, Elisabete; Würtz, Anne Mette L; Kühn, Tilman; Katzke, Verena; Trichopoulou, Antonia; Karakatsani, Anna; Vecchia, Carlo La; Masala, Giovanna; Tumino, Rosario; Panico, Salvatore; Sluijs, Ivonne; Skeie, Guri; Imaz, Liher; Petrova, Dafina; Ramón Quirós, J; Yohar, Sandra Milena Colorado; Jakszyn, Paula; Melander, Olle; Sonestedt, Emily; Andersson, Jonas; Wennberg, Maria; Aune, Dagfinn; Riboli, Elio; Schulze, Matthias B; di Angelantonio, Emanuele; Wareham, Nicholas J; Danesh, John; Forouhi, Nita G; Butterworth, Adam S; Key, Timothy J (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-27)
      <i>Background</i> - Epidemiological evidence indicates that diets rich in plant foods are associated with a lower risk of ischaemic heart disease (IHD), but there is sparse information on fruit and vegetable subtypes and sources of dietary fibre. This study examined the associations of major plant foods, their subtypes and dietary fibre with risk of IHD in the European Prospective Investigation into ...

    • Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study 

      Aglago, Elom K.; Schalkwijk, Casper G.; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Katzke, Verena; Johnson, Theron; Schulze, Matthias B.; Aleksandrova, Krasimira; Masala, Giovanna; Sieri, Sabina; Simeon, Vittorio; Tumino, Rosario; Macciotta, Alessandra; Bueno-De-Mesquita, Bas; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Jakszyn, Paula; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Perez-Cornago, Aurora; Mayén, Ana-Lucia; Weiderpass, Elisabete; Gunter, Marc J.; Heath, Alicia K.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
      Advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed by the non-enzymatic reaction between amino acids and reducing sugars, or dicarbonyls as intermediate compounds. Experimental studies suggest that AGEs may promote colorectal cancer, but prospective epidemiologic studies are inconclusive. We conducted a case–control study nested within a large European cohort. Plasma ...

    • Plasma elaidic acid level as biomarker of industrial trans fatty acids and risk of weight change: Report from the EPIC study 

      Chajès, Véronique; Biessy, Carine; Ferrari, Pietro; Romieu, Isabelle; Freisling, Heinz; Huybrechts, Inge; Scalbert, Augustin; Bueno-de-Mesquita, H. Bas; Romaguera, Dora; Gunter, Mark J.; Vineis, Paolo; Hansen, Camilla Plambeck; Jakobsen, Marianne Uhre; Clavel-Chapelon, Françoise; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Katzke, Verana; Neamat-Allah, Jasmine; Boeing, Heiner; Bachlechner, Ursula; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Pala, Valeria; Masala, Giovanna; Mattiello, Amalia; Skeie, Guri; Weiderpass, Elisabete; Agudo, Antonio; Huerta, José María; Sánchez, Mariá-José; Dorronsoro, Miren; Quirós, José Ramón; Johansson, Ingegerd; Winkvist, Anna; Sonested, Emily; Key, Timothy J.; Khaw, Kay-Tee; Wareham, Nicholas J.; Peeters, Petra H.M.; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-12)
      Background Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition ...

    • Pre-diagnostic circulating insulin-like growth factor-I and bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition 

      Lin, Crystal; Travis, Ruth C.; Appleby, Paul N.; Tipper, Sarah; Weiderpass, Elisabete; Chang-Claude, Jenny; Gram, Inger Torhild; Kaaks, Rudolf; Kiemeney, Lambertus A.; Ljungberg, Börje; Tumino, Rosario; Tjønneland, Anne; Roswall, Nina; Overvad, Kim; Boutron-Ruault, Marie-Christine; Manciniveri, Francesca Romana; Severi, Gianluca; Trichopoulou, Antonia; Masala, Giovanna; Sacerdote, Carlotta; Agnoli, Claudia; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Salamanca-Fernández, Elena; Chirlaque, Maria-Dolores; Ardanaz, Eva; Dorronsoro, Miren; Menéndez, Virginia; Luján-Barroso, Leila; Liedberg, Fredrik; Freisling, Heinz; Gunter, Marc; Aune, Dagfinn; Cross, Amanda J.; Riboli, Elio; Key, Timothy J.; Perez-Cornago, Aurora (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-04)
      Previous <i>in vitro</i> and case–control studies have found an association between the insulin‐like growth factor (IGF)‐axis and bladder cancer risk. Circulating concentrations of IGF‐I have also been found to be associated with an increased risk of several cancer types; however, the relationship between pre‐diagnostic circulating IGF‐I concentrations and bladder cancer has never been studied ...

    • Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: A cohort study 

      Romaguera, Dora; Ward, Heather; Wark, Petra A.; Vergnaud, Anne-Claire; Peeters, Petra H.; van Gils, Carla H.; Ferrari, Pietro; Fedirko, Veronika; Jenab, Mazda; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Hansen, Camilla Plambeck; Dahm, Christina Catherine; Buckland, Genevieve; Sánchez, María-José; Dorronsoro, Miren; Navarro, Carmen; Barricarte, Aurelio; Key, Timothy J.; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Masala, Giovanna; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Siersema, Peter D.; Ohlsson, Bodil; Jirström, Karin; Wennberg, Maria; Nilsson, Lena Maria; Weiderpass, Elisabete; Kühn, Tilman; Katzke, Verena A.; Khaw, Kay-Tee; Wareham, Nicholas J.; Tjønneland, Anne; Boeing, Heiner; Quirós, José Ramón; Gunter, Mark J.; Riboli, Eilo; Norat, Teresa (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-07)
      Background: Cancer survivors are advised to follow lifestyle recommendations on diet, physical activity, and body fatness proposed by the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) for cancer prevention. Previous studies have demonstrated that higher concordance with these recommendations measured using an index score (the WCRF/AICR score) was associated with ...

    • Prediagnostic Blood Selenium Status and Mortality among Patients with Colorectal Cancer in Western European Populations 

      Baker, Jacqueline Roshelli; Umesh, Sushma; Jenab, Mazda; Schomburg, Lutz; Tjønneland, Anne; Olsen, Anja; Marie-Christine, Boutron-Ruault; Rothwell, Joseph A.; Severi, Gianluca; Katzke, Verena; Johnson, Theron; Schulze, Matthias B.; Masala, Giovanna; Agnoli, Claudia; Simeon, Vittorio; Tumino, Rosario; Bueno-De-Mesquita, Bas; Gram, Inger Torhild; Skeie, Guri; Bonet, Catalina; RodrÍguez-Barranco, Miguel; Houerta, José María; Gylling, Björn; Van Guelpen, Bethany; Perez-Cornago, Aurora; Aglago, Elom; Freisling, Heinz; Weiderpass, Elisabete; Cross, Amanda J.; Heath, Alicia K.; Hughes, , David J.; Fedirko, Veronika (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      A higher selenium (Se) status has been shown to be associated with lower risk for colorectal cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied. The associations of prediagnostic circulating Se status (as indicated by serum Se and selenoprotein P (SELENOP) measurements) with overall and CRC-specific mortality were estimated using multivariable Cox proportional ...

    • Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition 

      Perez-Cornago, Aurora; Appleby, Paul N.; Tipper, Sarah; Key, Timothy J.; Allen, Naomi E.; Nieters, Alexandra; Vermeulen, Roel; Roulland, Sandrine; Casabonne, Delphine; Kaaks, Rudolf; Fortner, Renée T.; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Klinaki, Eleni; Hansen, Louise; Tjønneland, Anne; Bonnet, Fabrice; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Pala, Valeria; Masala, Giovanna; Sacerdote, Carlotta; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Dorronsoro, Miren; Quirós, J. Ramón; Barricarte, Aurelio; Gavrila, Diana; Agudo, Antonio; Borgquist, Signe; Rosendahl, Ann H.; Melin, Beatrice; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc; Riboli, Elio; Vineis, Paolo; Travis, Ruth C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-27)
      Insulin-like growth factor (IGF)-I has cancer promoting activities. However, the hypothesis that circulating IGF-I concentration is related to risk of lymphoma overall or its subtypes has not been examined prospectively. IGF-I concentration was measured in pre-diagnostic plasma samples from a nested case–control study of 1,072 cases of lymphoid malignancies and 1,072 individually matched controls ...

    • Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study 

      Hughes, David J.; Schomburg, Lutz; Jenab, Mazda; Biessy, Carine; Méplan, Catherine; Moskal, Aurelie; Sun, Qian; Demircan, Kamil; Fedirko, Veronika; Weiderpass Vainio, Elisabete; Mukhtar, Maryam; Olsen, Anja; Tjønneland, Anne; Overvad, Kim; Schulze, Matthias; Nøst, Therese Haugdahl; Skeie, Guri; Olsen, Karina Standahl; Ricceri, Fulvio; Grioni, Sara; Palli, Domenico; Masala, Giovanna; Tumino, Rosario; Pasanisi, Fabrizio; Amiano, Pilar; Colorado Yohar, Sandra M.; Agudo, Antonio; Sánchez, Maria-Jose; Ardanaz, Eva; Sund, Malin; Andersson, Anne; Perez-Cornago, Aurora; Travis, Ruth; Heath, Alicia K.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-01)
      Selenium (Se) may help prevent breast cancer (BC) development. Owing to limited observational evidence, we investigated whether prediagnostic Se status and/or variants in the selenoprotein genes are associated with BC risk in a large European cohort. Se status was assessed by plasma measures of Se and its major circulating proteins, selenoprotein P (SELENOP) and glutathione peroxidase 3 (GPX3), in ...

    • Prospective analysis of circulating metabolites and breast cancer in EPIC 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Gicquiau, Audrey; Achaintre, David; Scalbert, Augustin; Ferrari, Pietro; Romieu, Isabelle; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Fournier, Agnès; Rothwell, Joseph A.; Severi, Gianluca; Kühn, Tilman; Fortner, Renée Turzanski; Boeing, Heiner; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; van Gils, Carla H.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Schmidt, Julie A.; Travis, Ruth C.; Riboli, Elio; Tsilidis, Konstantinos K.; Christakoudi, Sofia; Gunter, Mark J.; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <i>Background</i> - Metabolomics is a promising molecular tool to identify novel etiologic pathways leading to cancer. Using a targeted approach, we prospectively investigated the associations between metabolite concentrations in plasma and breast cancer risk.<p> <p><i>Methods</i> - A nested case-control study was established within the European Prospective Investigation into Cancer cohort, which ...

    • A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC 

      Papadimitriou, Nikos; Bouras, Emmanouil; van den Brandt, Piet A.; Muller, David C.; Papadopoulou, Areti; Heath, Alicia K.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Ferrari, Pietro; Weiderpass, Elisabete; Boeing, Heiner; Bastide, Nadia; Merritt, Melissa A.; Lopez, David S.; Bergmann, Manuela M.; Perez-Cornago, Aurora; Schulze, Matthias; Skeie, Guri; Srour, Bernard; Eriksen, Anne Kirstine; Boden, Stina; Johansson, Ingegerd; Nøst, Therese Haugdahl; Lukic, Marko; Ricceri, Fulvio; Ericson, Ulrika; Huerta, José-Maria; Dahm, Christina C.; Agnoli, Claudia; Amiano, Pilar; Tjønneland, Anne; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Ardanaz, Eva; Berntsson, Jonna; Sánchez, Maria-Jose; Tumino, Rosario; Panico, Salvatore; Katzke, Verena; Jakszyn, Paula; Masala, Giovanna; Derksen, Jeroen W.G.; Quirós, J. Ramón; Severi, Gianluca; Cross, Amanda J.; Riboli, Ellio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-24)
      Background & Aims - Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.<p> <p>Methods - The association ...

    • Prospective evaluation of 92 serum protein biomarkers for early detection of ovarian cancer 

      Mukama, Trasias; Fortner, Renée Turzanski; Katzke, Verena; Hynes, Lucas Cory; Petrera, Agnese; Hauck, Stefanie M.; Johnson, Theron; Schulze, Matthias; Schiborn, Catarina; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Overvad, Kim; Pérez, María José Sánchez; Crous-Bou, Marta; Chirlaque, María-Dolores; Amiano, Pilar; Ardanaz, Eva; Watts, Eleanor L.; Travis, Ruth C.; Sacerdote, Carlotta; Grioni, Sara; Masala, Giovanna; Signoriello, Simona; Tumino, Rosario; Gram, Inger Torhild; Sandanger, Torkjel M; Sartor, Hanna; Lundin, Eva; Idahl, Annika; Heath, Alicia K.; Dossus, Laure; Weiderpass, Elisabete; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-14)
      BACKGROUND: CA125 is the best available yet insufficiently sensitive biomarker for early detection of ovarian cancer. There is a need to identify novel biomarkers, which individually or in combination with CA125 can achieve adequate sensitivity and specificity for the detection of earlier-stage ovarian cancer.<p> <p>METHODS: In the European Prospective Investigation into Cancer and Nutrition ...