Blar i forfatter "Masala, Giovanna"

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    • Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Boeing, Heiner; Ferrari, Pietro; Merritt, Melissa A.; Rostgaard-Hansen, Agnetha L.; Tjønneland, Anne; Overvad, Kim; Katzke, Verena; Srour, Bernard; Masala, Giovanna; Sacerdote, Carlotta; Ricceri, Fulvio; Pasanisi, Fabrizio; Bueno-de-Mesquita, Bas; Downward, George S.; Skeie, Guri; Sandanger, Torkjel M; Crous-Bou, Marta; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Drake, Isabel; Johansson, Mikael; Johansson, Ingegerd; Key, Tim; Papadimitriou, Nikos; Riboli, Elio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327 790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox regression yielded adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per SD higher intake/day of ...

    • Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries 

      Tong, Tammy Y. N.; Clarke, Robert Michael; Schmidt, Julie A.; Huybrechts, Inge; Noor, Urwah; Forouhi, Nita G.; Imamura, Fumiaki; Travis, Ruth C.; Weiderpass Vainio, Elisabete; Aleksandrova, Krasimira; Dahm, Christina C.; van der Schouw, Yvonne T.; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Kaaks, Rudolf; Katzke, Verena; Schiborn, Catarina; Schulze, Matthias B.; Mayen-Chacon, Ana-Lucia; Masala, Giovanna; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Sacerdote, Carlotta; Boer, Jolanda M. A.; Verschuren, W. M. Monique; Brustad, Magritt; Nøst, Therese Haugdahl; Crous-Bou, Marta; Petrova, Dafina; Amiano, Pilar; Huerta, José María; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Johansson, Kristina; Lindvall, Kristina; Aglago, Elom K.; Heath, Alicia K.; Butterworth, Adam S.; Danesh, John; Key, Timothy J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-07)
      Purpose - Previously reported associations of protein-rich foods with stroke subtypes have prompted interest in the assessment of individual amino acids. We examined the associations of dietary amino acids with risks of ischaemic and haemorrhagic stroke in the EPIC study.<p> <p>Methods - We analysed data from 356,142 participants from seven European countries. Dietary intakes of 19 individual ...

    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...

    • Dietary folate intake and pancreatic cancer risk: Results from the European prospective investigation into cancer and nutrition 

      Park, Jin Young; Bueno-de-Mesquita, Hendrik Bastiaan; Ferrari, Pietro; Weiderpass, Elisabete; de Batlle, Jordi; Tjønneland, Anne; Kyrø, Cecilie; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kritikou, Maria; Masala, Giovanna; Pala, Valeria; Tumino, Rosario; Panico, Salvatore; Peeters, Petra H.; Skeie, Guri; Merino, Susana; Duell, Eric J.; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Ardanaz, Eva; Gylling, Björn; Schneede, Jørn; Ericson, Ulrika; Sternby, Hanna; Khaw, Kay-Tee; Bradbury, Kathryn E.; Huybrechts, Inge; Aune, Dagfinn; Vineis, Paolo; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-04)
      Pancreatic cancer (PC) has an exceptionally low survival rate and primary prevention strategies are limited. Folate plays an important role in one‐carbon metabolism and has been associated with the risk of several cancers, but not consistently with PC risk. We aimed to investigate the association between dietary folate intake and PC risk, using the standardised folate database across 10 European ...

    • Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort 

      Gil-Lespinard, Mercedes; Castañeda, Jazmín; Almanza-Aguilera, Enrique; Gómez, Jesús Humberto; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Lasheras, Cristina; Molina-Montes, Esther; Huerta, José María; Barricarte, Aurelio; Amiano, Pilar; Sonestedt, Emily; da Silva, Marisa Eleonor; Johansson, Ingegerd; Hultdin, Johan; May, Anne M.; Forouhi, Nita G.; Heath, Alicia K.; Freisling, Heinz; Weiderpass, Elisabete; Scalbert, Augustin; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)
      Polyphenols are bioactive compounds from plants with antioxidant properties that may have a protective role against body weight gain, with adipose tissue and systemic oxidative stress as potential targets. We aimed to investigate the dietary intake of individual polyphenols and their association with 5-year body weight change in a sub-cohort of the European Prospective Investigation into Cancer and ...

    • Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study 

      Ana-Lucia, Mayén; Aglago, Elom K.; Knaze, Viktoria; Cordova, Reynalda; Schalkwijk, Casper G.; Wagner, Karl-Heinz; Aleksandrova, Krasimira; Fedirko, Veronika; Keski-Rahkonen, Pekka; Leitzmann, Michael F.; Katzke, Verena; Srour, Bernard; Schulze, Matthias B.; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Bueno-de-Mesquita, Bas; Brustad, Magritt; Agudo, Antonio; López, María Dolores Chirlaque; Amiano, Pilar; Ohlsson, Bodil; Ramne, Stina; Aune, Dagfinn; Weiderpass, Elisabete; Jenab, Mazda; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-25)
      Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of AGEs intake in liver cancer etiology. We examined the association between dietary AGEs and the risk of hepatobiliary cancers in the European Prospective Investigation into Cancer ...

    • Dietary intake of trans fatty acids and breast cancer risk in 9 European countries 

      Matta, Michèle; Huybrechts, Inge; Biessy, Carine; Casagrande, Corinne; Yammine, Sahar; Fournier, Agnès; Olsen, Karina Standahl; Lukic, Marco; Gram, Inger Torhild; Ardanaz, Eva; Sánchez, Maria-José; Dossus, Laure; Fortner, Renée T.; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Amiano, Pilar; Agudo, Antonio; Colorado-Yohar, Sandra; Guirós, J. Ramón; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Pala, Valeria; Sacerdote, Carlotta; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C.; Rosendahl, Ann H.; Borgquist, Signe; Wennberg, Maria; Heath, Alicia K.; Aune, Dagfinn; Schmidt, Julie; Weiderpass, Elisabete; Chajes, Veronique; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      Background - Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted.<p> <p>Methods - In the European Prospective Investigation into Cancer and Nutrition ...

    • DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility 

      Ambatipudi, Srikant; Horvath, Steve; Perrier, Flavie; Cuenin, Cyrille; Hernandez-Vargas, Hector; Le Calvez-Kelm, Florence; Durand, Geoffroy; Byrnes, Graham; Ferrari, Pietro; Bouaoun, Liacine; Sklias, Athena; Chajès, Véronique; Overvad, Kim; Severi, Gianluca; Baglietto, Laura; Clavel-Chapelon, Françoise; Kaaks, Rudolf; Barrdahl, Myrto; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Naska, Androniki; Masala, Giovanna; Agnoli, Claudia; Polidoro, Silvia; Tumino, Rosario; Panico, Salvatore; Dollé, Martijn; Peeters, Petra H.M.; Onland-Moret, N. Charlotte; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Weiderpass, Elisabete; Quirós, José Ramón; Agudo, Antonio; Rodriguez-Barranco, Miguel; Huerta Castaño, José María; Barricarte, Aurelio; Fernández, Ander Matheu; Travis, Ruth C.; Vineis, Paolo; Muller, David C.; Riboli, Elio; Gunter, Marc; Romieu, Isabelle; Herceg, Zdenko (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-28)
      Aim of the study: A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as ‘epigenetic clock’, has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based ...

    • Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: a Prospective Study and Meta-Analysis 

      Mori, Nagisa; Keski-Rahkonen, Pekka; Gicquiau, Audrey; Rinaldi, Sabina; Dimou, Niki; Harlid, Sophia; Harbs, Justin; Van Guelpen, Bethany; Aune, Dagfinn; Cross, Amanda J.; Tsilidis, Konstantinos K.; Severi, Gianluca; Kvaskoff, Marina; Fournier, Agnès; Kaaks, Rudolf; Fortner, Renée Turzanski; Schulze, Matthias B.; Jakszyn, Paula; Sánchez, Maria-José; Colorado-Yohar, Sandra M.; Ardanaz, Eva; Travis, Ruth; Watts, Eleanor L.; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Buenode-Mesquita, bas; Gram, Inger Torhild; Waaseth, Marit; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-28)
      Background - Observational studies have consistently reported that postmenopausal hormone therapy use is associated with lower colon cancer risk, but epidemiologic studies examining the associations between circulating concentrations of endogenous estrogens and colorectal cancer have reported inconsistent results.<p> <p>Methods - We investigated the associations between circulating concentrations ...

    • Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis 

      van Veldhoven, Karin; Polidoro, Silvia; Baglietto, Laura; Severi, Gianluca; Sacerdote, Carlotta; Panico, Salvatore; Mattiello, Amalia; Palli, Domenico; Masala, Giovanna; Krogh, Vittorio; Agnoli, Claudia; Tumino, Rosario; Frasca, Graziella; Flower, Kirsty; Curry, Ed; Orr, Nicholas; Tomczyk, Katarzyna; Jones, Michael E.; Ashworth, Alan; Swerdlow, Anthony; Chadeau-Hyam, Marc; Lund, Eiliv; Garcia-Closas, Montserrat; Sandanger, Torkjel M; Flanagan, James M.; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-04)
      Background: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast cancer. We report on three independent prospective nested case-control studies from the European ...

    • Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort 

      Engeset, Dagrun; Braaten, Tonje; Teucher, Birgit; Kuhn, Tilman; Bueno-de-Mesquita, HB; Leenders, Max; Agudo, Antonio; Bergmann, Manuela M; Valanou, Elisavet; Naska, Androniki; Trichopoulou, Antonia; Key, Timothy J; Crowe, Francesca L; Overvad, Kim; Sonestedt, Emily; Mattiello, Amalia; Peeters, Petra H; Wennberg, Maria; Jansson, Jan Håkan; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Li, Kuanrong; Barricarte, Aurelio; Ward, Heather; Riboli, Elio; Agnoli, Claudia; Huerta, Jose Maria; Sanchez, Maria-Jose; Tumino, Rosario; Altzibar, Jone M; Vineis, Paolo; Masala, Giovanna; Ferrari, Pietro; Muller, David C; Johansson, Mattias; Luisa Redondo, M; Tjønneland, A; Olsen, Anja; Olsen, Karina Standahl; Brustad, Magritt; Skeie, Guri; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Flavonoid and lignan intake and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort 

      Molina-Montes, Esther; Sánchez, María-José; Zamora-Ros, Raul; Bueno-de-Mesquita, H. Bas; Wark, Petra A.; Obon-Santacana, Mireia; Kühn, Tilman; Katzke, Verena; Travis, Ruth C.; Ye, Weimin; Sund, Malin; Naccarati, Alessio; Mattiello, Amalia; Krogh, Vittorio; Martorana, Caterina; Masala, Giovanna; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Quirós, José Ramón; Weiderpass, Elisabete; Åsli, Lene Angel; Skeie, Guri; Ericson, Ulrika; Sonestedt, Emily; Peeters, Petra H.; Romieu, Isabelle; Scalbert, Augustin; Overvad, Kim; Clemens, Matthias; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Vidalis, Pavlos; Khaw, Kay-Tee; Wareham, Nick; Olsen, Anja; Tjønneland, Anne; Boutroun-Rualt, Marie-Christine; Clavel-Chapelon, Françoise; Cross, Amanda J.; Lu, Yunxia; Riboli, Elio; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-10)
      Despite the potential cancer preventive effects of flavonoids and lignans, their ability to reduce pancreatic cancer risk has not been demonstrated in epidemiological studies. Our aim was to examine the association between dietary intakes of flavonoids and lignans and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. A total of 865 exocrine ...

    • Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study 

      Hanley-Cook, Giles T.; Huybrechts, Inge; Biessy, Carine; Remans, Roseline; Kennedy, Gina; Deschasaux-Tanguy, Mélanie; Murray, Kris A.; Touvier, Mathilde; Skeie, Guri; Kesse-Guyot, Emmanuelle; Argaw, Alemayehu; Casagrande, Corinne; Nicolas, Geneviève; Vineis, Paolo; Millett, Christopher J.; Weiderpass, Elisabete; Ferrari, Pietro; Dahm, Christina C.; Bueno-De-Mesquita, H. Bas; Sandanger, Torkjel M; Ibsen, Daniel B.; Freisling, Heinz; Ramne, Stina; Jannasch, Franziska; van der Schouw, Yvonne T.; Schulze, Matthias B.; Tsilidis, Konstantinos K.; Tjønneland, Anne; Ardanaz, Eva; Bodén, Stina; Cirera, Lluís; Gargano, Giuliana; Halkjær, Jytte; Jakszyn, Paula; Johansson, Ingegerd; Katzke, Verena; Masala, Giovanna; Panico, Salvatore; Rodriguez-Barranco, Miguel; Sacerdote, Carlotta; Srour, Bernard; Tumino, Rosario; Riboli, Elio; Gunter, Marc J.; Jones, Andrew D.; Lachat, Carl (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background<p> <p>Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets ...

    • Genetically determined reproductive aging and coronary heart disease: a bidirectional two-sample Mendelian Randomization 

      Dam, Veerle; Onland-Moret, N. Charlotte; Burgess, Stephen; Chirlaque, Maria Dolores; Peters, Sanne A.E.; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Oliver-Williams, Clare; Wood, Angela M.; Tjønneland, Anne; Dahm, Christina C; Overvad, Kim; Boutron-Rualt, Marie-Christine; Schulze, Matthias B.; Trichopoulou, Antonia; Ferrari, Pietro; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Matullo, Giuseppe; Panico, Salvatore; Boer, Jolanda M. A.; Verschuren, W.M. Monique; Waaseth, Marit; Pérez, María José Sánchez; Amiano, Pilar; Imaz, Liher; Moreno-Iribas, Conchi; Melander, Olle; Harlid, Sophia; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Riboli, Elio; Santiuste, Carmen; Kaaks, Rudolf; Katzke, Verena; Langenberg, Claudia; Wareham, Nicholas J.; Schunkert, Heribert; Erdmann, Jeanette; Willenborg, Christina; Hengstenberg, Christian; Kleber, Marcus E.; Delgado, Graciela; März, Winfried; Kanoni, Stavroula; Dedoussis, George; Deloukas, Panos; Nikpay, Majid; McPherson, Ruth; Scholz, Markus; Teren, Andrej; Butterworth, Adam S.; van der Schouw, Yvonne T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-20)
      Background: Accelerated reproductive aging, in women indicated by early natural menopause, is associated with increased coronary heart disease (CHD) risk in observational studies. Conversely, an adverse CHD risk profile has been suggested to accelerate menopause.<p> <p>Objectives: To study the direction and evidence for causality of the relationship between reproductive aging and (non-)fatal CHD ...

    • Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohort 

      Ose, Jennifer; Fortner, Renée T; Schock, Helena; Peeters, Petra H.; Onland-Moret, N. Charlotte; Bueno-de-Mesquita, H. Bas; Weiderpass, Elisabete; Gram, Inger Torhild; Overvad, Kim; Tjønneland, Anne; Dossus, Laure; Fournier, Agnes; Baglietto, Laura; Trichopoulou, Antonia; Benetou, Vassiliki; Trichopoulos, Dimitrios; Boeing, Heiner; Masala, Giovanna; Krogh, Vittorio; Matiello, Amalia; Tumino, Rosaria; Popovic, Maja; Obón-Santacana, Mireia; Larrañaga, Nerea; Ardanaz, Eva; Sánchez, María-José; Menéndez, Virginia; Chirlaque, María-Dolores; Travis, Ruth C.; Khaw, Kay-Tee; Brändstedt, Jenny; Idahl, Annika; Lundin, Eva; Rinaldi, Sabina; Kuhn, Elisabetta; Romieu, Isabelle; Gunter, Marc J.; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-04)
      Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics ...

    • Isocaloric substitution of carbohydrates with protein: The association with weight change and mortality among patients with type 2 diabetes 

      Campmans-Kuijpers, Marjo J.E.; Sluijs, Ivonne; Nöthlings, Ute; Freisling, Heinz; Overvad, Kim; Weiderpass, Elisabete; Fagherazzi, Guy; Kühn, Tilman; Katzke, Verena A.; Mattiello, Amalia; Sonestedt, Emily; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Spijkerman, Annemieke M.W.; Barricarte, Aurelio; Ricceri, Fulvio; Chamosa, Saioa; Johansson, Ingegerd; Winkvist, Anna; Tjønneland, Anne; Sluik, Diewertje; Boeing, Heiner; Beulens, Joline W.J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-18)
      Background: The health impact of dietary replacement of carbohydrates with protein for patients with type 2 diabetes is still debated. This study aimed to investigate the association between dietary substitution of carbohydrates with (animal and plant) protein and 5-year weight change, and all-cause and cardiovascular (CVD) mortality risk in patients with type 2 diabetes. <p>Methods: The study ...

    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...

    • Long-term weight change and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Ellingjord-Dale, Merete; Christakoudi, Sofia; Weiderpass, Elisabete; Panico, Salvatore; Dossus, Laure; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Gram, Inger Torhild; Skeie, Guri; Rosendahl, Ann H.; Sund, Malin; Key, Tim; Ferrari, Pietro; Gunter, Marc; Heath, Alicia K; Tsilidis, Konstantinos K; Riboli, Eilo; Sánchez, Maria-Jose; Lopez, Maria-Dolores Chirlaque; Peppa, Eleni; Trichopoulou, Antonia; Martimianaki, Georgia; Agudo, Antonio; Santiuste, Carmen; Ardanaz, Eva; Amiano, Pilar; Boutron-Ruault, Marie-Chiristine; Simeon, Vittorio; Berrino, Franco; Tumino, Rosario; Severi, Gianluca; Stocks, Tanja; Turzanski-Fortner, Renée; Rylander, Charlotta; Aune, Dagfinn; Dahm, Christina Catherine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
      Background: The role of obesity and weight change in breast-cancer development is complex and incompletely understood. We investigated long-term weight change and breast-cancer risk by body mass index (BMI) at age 20 years, menopausal status, hormone replacement therapy (HRT) and hormone-receptor status.<p><p> Methods: Using data on weight collected at three different time points from women ...

    • Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study 

      Moskal, Aurelie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T.; Jenab, Mazda; Ferrari, Pietro; Tjønneland, Anne; Petersen, Kristina E N; Dahm, Christina C; Hansen, Camilla Plambeck; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Cadeau, Claire; Kuhn, Tilman; Katzke, Verena; Iqbal, Khalid; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Masala, Giovanna; de Magistris, Maria Santucci; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Peeters, Petra H; Bueno-de-Mesquita, Bas H; Engeset, Dagrun; Licaj, Idlir; Skeie, Guri; Ardanaz, Eva; Buckland, Genevieve; Castaño, José María Huerta; Quirós, José R.; Amiano, Pilar; Molina-Portillo, Elena; Winkvist, Anna; Myte, Robin; Ericson, Ulrika; Sonestedt, Emily; Perez-Cornago, Aurora; Wareham, Nick; Khaw, Kay-Tee; Huybrechts, Inge; Tsilidis, Konstantinos K; Ward, Heather; Gunter, Marc J; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-20)
      Background: Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/ nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. <p>Methods: Among 477 312 participants, ...

    • Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia 

      Berndt, Sonja I.; Camp, Nicola J.; Skibola, Christine F.; Vijai, Joseph; Wang, Zhaoming; Gu, Jian; Nieters, Alexandra; Kelly, Rachel S; Smedby, Karin E.; Monnereau, Alain; Cozen, Wendy; Cox, Angela; Wang, Sophia S.; Lan, Qing; Teras, Lauren R; Machado, Moara; Yeager, Meredith; Brooks-Wilson, Angela R.; Hartge, Patricia; Purdue, Mark P.; Birmann, Brenda M.; Vajdic, Claire M.; Cocco, Pierluigi; Zhang, Yawei; Giles, Graham G.; Zeleniuch-Jacquotte, Anne; Lawrence, Charles; Montalvan, Rebecca; Burdett, Laurie; Hutchinson, Amy; Ye, Yuanqing; Call, Timothy G.; Shanafelt, Tait D.; Novak, Anne J.; Kay, Neil E.; Liebow, Mark; Cunningham, Julie M.; Allmer, Cristine; Hjalgrim, Henrik; Adami, Hans-Olov; Melbye, Mads; Glimelius, Bengt; Chang, Ellen T.; Glenn, Martha; Curtin, Karen; Cannon-Albright, Lisa A.; Diver, W Ryan; Link, Brian K.; Weiner, George J.; Conde, Lucia; Bracci, Paige M.; Riby, Jacques; Arnett, Donna K.; Zhi, Degui; Leach, Justin M.; Holly, Elizabeth A.; Jackson, Rebecca D.; Tinker, Lesley F.; Benavente, Yolanda; Sala, Nuria; Casabonne, Delphine; Becker, Nikolaus; Boffetta, Paolo; Brennan, Paul; Foretova, Lenka; Maynadie, Marc; McKay, James; Staines, Anthony; Chaffee, Kari G.; Achenbach, Sara J.; Vachon, Celine M.; Goldin, Lynn R.; Strom, Sara S.; Leis, Jose F.; Weinberg, J. Brice; Caporaso, Neil E.; Norman, Aaron D.; De Roos, Anneclaire J.; Morton, Lindsay M.; Severson, Richard K.; Riboli, Elio; Vineis, Paolo; Kaaks, Rudolph; Masala, Giovanna; Weiderpass, Elisabete; Chirlaque, Maria-Dolores; Vermeulen, Roel C.H.; Travis, Ruth C.; Southey, Melissa C.; Milne, Roger L.; Albanes, Demetrius; Virtamo, Jarmo; Weinstein, Stephanie; Clavel, Jacqueline; Zheng, Tongzhang; Holford, Theodore R.; Villano, Danylo J.; Maria, Ann; Spinelli, John J.; Gascoyne, Randy D.; Connors, Joseph M.; Bertrand, Kimberly A.; Giovannucci, Edward; Kraft, Peter; Kricker, Anne; Turner, Jenny; Ennas, Maria Grazia; Ferri, Giovanni M.; Miligi, Lucia; Liang, Liming; Ma, Baoshan; Huang, Jinyan; Crouch, Simon; Park, Ju-Hyun; Chatterjee, Nilanjan; North, Kari E.; Snowden, John A.; Wright, Josh; Fraumeni, Joseph F.; Offit, Kenneth; Wu, Xifeng; De Sanjose, Silvia; Cerhan, James R.; Chanock, Stephen J.; Rothman, Nathaniel; Slager, Susan L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-09)
      Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and identify common loci associated with risk, we conducted a meta-analysis of four genome-wide association studies (GWAS) composed of 3,100 cases and 7,667 controls with follow-up replication in 1,958 cases and 5,530 controls. Here we report three new ...