Now showing items 41-59 of 59

    • Localization of Staphylococcus aureus in tissue from the nasal vestibule in healthy carriers 

      Hanssen, Anne-Merethe; Kindlund, Bert; Stenklev, Niels Christian; Furberg, Anne-Sofie; Fismen, Silje; Olsen, Renate Slind; Johannessen, Mona; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-05)
      <p><b>Background:</b> Colonization of the body is an important step in Staphylococcus aureus infection. S. aureus colonizes skin and mucous membranes in humans and several animal species. One important ecological niche of S. aureus is the anterior nares. More than 60% of the S. aureus in the nose are found in vestibulum nasi. Our aim was to describe the localization of S. aureus in nasal tissue ...
    • Multilocus Sequence Typing of Genital Chlamydia trachomatis in Norway Reveals Multiple New Sequence Types and a Large Genetic Diversity 

      Gravningen, Kirsten Midttun; Christerson, Linus; Furberg, Anne-Sofie; Simonsen, Gunnar Skov; Ödman, Kristina; Ståhlsten, Anna; Herrmann, Björn (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The Chlamydia trachomatis incidence rate in Finnmark, the most northern and sparsely populated county in Norway, has been twice the national average. This population based cross-sectional study among Finnmark high school students had the following aims: i) to examine distribution of multilocus sequence types (STs) of C. trachomatis in a previously unmapped area, ii) to compare chlamydia genetic ...
    • Obesity and Staphylococcus aureus Nasal Colonization among Women and Men in a General Population 

      Olsen, Karina; Danielsen, Kjersti; Wilsgaard, Tom; Sangvik, Maria; Sollid, Johanna U. Ericson; Thune, Inger; Eggen, Anne Elise; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Obesity and diabetes mellitus (DM) have been linked to increased risk of infections, and Staphylococcus aureus nasal colonization is a major risk factor for developing infections with the microbe. We therefore sought to find whether body mass index (BMI) and waist circumference (WC) could be associated with S. aureus colonization independent of DM. Methodology: S. aureus colonization ...
    • Ovarian hormones and reproductive risk factors for breast cancer in premenopausal women : the Norwegian EBBA-I study 

      Iversen, Anita; Thune, Inger; McTiernan, Anne; Emaus, Aina; Finstad, Sissi Espetvedt; Flote, Vidar Gordon; Wilsgaard, Tom; Lipson, Susan; Ellison, Peter T; Jasienska, Grazyna; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Ovarian hormones, parity and length of ‘menarche-to-first birth’ time interval are known risk factors for breast cancer, yet the associations between 17β-estradiol, progesterone and these reproductive factors remain unclear. A total of 204 women (25–35 years) who participated in the Norwegian EBBA-I study collected daily saliva samples for one complete menstrual cycle, and filled in a reproductive ...
    • Overweight and Weight Gain Predict Psoriasis Development in a Population-based Cohort 

      Danielsen, Kjersti; Wilsgaard, Tom; Olsen, Anne Olaug; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-07)
      Overweight is a proposed risk factor for psoriasis. How­ever, evidence from prospective studies is limited. The aim of this study was to investigate the association be­tween overweight, weight gain and risk of psoriasis, and potential synergism with smoking, within a population-based cohort including 8,752 individuals followed from 1994 up to 2008. There was a 32% increased odds of psoriasis from a ...
    • The peer effect on pain tolerance 

      Engebretsen, Solveig; Frigessi, Arnoldo; Engø-Monsen, Kenth; Furberg, Anne-Sofie; Stubhaug, Audun; De Blasio, Birgitte Freiesleben; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-19)
      Background and aims:<br> Twin studies have found that approximately half of the variance in pain tolerance can be explained by genetic factors, while shared family environment has a negligible effect. Hence, a large proportion of the variance in pain tolerance is explained by the (non-shared) unique environment. The social environment beyond the family is a potential candidate for explaining some ...
    • Polymorphisms in the estrogen receptor alpha gene (ESR1), daily cycling estrogen and mammographic density phenotypes 

      Fjeldheim, Frøydis Nyborg; Frydenberg, Hanne; Flote, Vidar Gordon; McTiernan, Anne; Furberg, Anne-Sofie; Ellison, Peter T.; Barrett, Emily S.; Wilsgaard, Tom; Jasienska, Grazyna; Ursin, Giske; Wist, Erik; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-07)
      Background: Single nucleotide polymorphisms (SNPs) involved in the estrogen pathway and SNPs in the estrogen receptor alpha gene (ESR1 6q25) have been linked to breast cancer development, and mammographic density is an established breast cancer risk factor. Whether there is an association between daily estradiol levels, SNPs in ESR1 and premenopausal mammographic density phenotypes is unknown. Methods: ...
    • A population-based study of inflammatory mechanisms and pain sensitivity 

      Schistad, Ellina Iordanova; Kong, Xiang Yi; Furberg, Anne-Sofie; Bäckryd, Emmanuel; Grimnes, Guri; Emaus, Nina; Rosseland, Leiv Arne; Gordh, Torsten; Stubhaug, Audun; Engdahl, Bo Lars; Halvorsen, Bente Evy; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-21)
      Two recent studies suggest that experimental pain sensitivity is associated with low-grade systemic inflammation. However, only 2 biomarkers have been identified, and the studies were conducted in adult individuals where confounding effects of comorbid diseases cannot be excluded. We therefore tested associations between pain sensitivity and 119 inflammation-related serum biomarkers in 827 healthy ...
    • Prevalence and population structure of Staphylococcus aureus nasal carriage in healthcare workers in a general population. The Tromsø Staph and Skin Study 

      Olsen, Karina; Sangvik, Maria; Simonsen, Gunnar Skov; Sollid, Johanna U Ericson; Sundsfjord, Arnfinn; Thune, Inger; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Healthcare workers (HCWs) may be a reservoir for Staphylococcus aureus transmission to patients. We examined whether HCW status is associated with S. aureus nasal carriage and population structure (spa types) in 1302 women (334 HCWs) and 977 men (71 HCWs) aged 30–69 years participating in the population-based Tromsø Study in 2007–2008. Multivariable logistic regression models were used. While no ...
    • Prevalence of accelerometer-measured physical activity in adolescents in Fit Futures – part of the Tromsø Study 

      Beldo, Sigurd; Morseth, Bente; Christoffersen, Tore; Halvorsen, Peder Andreas; Hansen, Bjørge Hermann; Furberg, Anne-Sofie; Ekelund, Ulf; Horsch, Alexander (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-17)
      <i>Background</i> - Previous studies show large variations in physical activity (PA) levels among adolescents. However, the number of studies is limited and even fewer studies have assessed PA in adolescents by accelerometer devices. This study aimed to describe accelerometer-measured PA levels in adolescents in a population-based cohort in Northern Norway.<p> <p><i>Methods</i> - In 611 students ...
    • The relation between birthweight, childhood body mass index, and overweight and obesity in late adolescence: a longitudinal cohort study from Norway, The Tromsø Study, Fit Futures 

      Evensen, Elin Kristin; Emaus, Nina; Kokkvoll, Ane Sofie; Wilsgaard, Tom; Furberg, Anne-Sofie; Skeie, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-22)
      <i>Objectives</i>: Childhood overweight/obesity is associated with later overweight/obesity. However, the association between birth weight and later overweight/obesity has not been established. The aim of this study was to investigate the relation between both birth weight and childhood body mass index (BMI), and adolescent overweight/obesity in a Norwegian population.<p> <p><i>Methods</i>: ...
    • Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations 

      Flatby, Helene Marie; Rasheed, Humaira; Ravi, Anuradha; Thomas, Laurent; Liyanarachi, Kristin Vardheim; Afset, Jan Egil; DeWan, Andrew; Brumpton, Ben Michael; Hveem, Kristian; Åsvold, Bjørn Olav; Simonsen, Gunnar Skov; Furberg, Anne-Sofie; Damås, Jan Kristian; Solligård, Erik; Rogne, Tormod (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-09)
      Objective: Lower respiratory tract infections (LRTIs) are a leading cause of morbidity and mortality worldwide. Few studies have previously investigated the genetic susceptibility and potential risk factors for LRTI. Methods: We used data from UK Biobank, HUNT, and FinnGen, to conduct a genome-wide association study (GWAS). Cases were subjects hospitalized with LRTI, and controls were subjects with ...
    • Serum perfluoroalkyl substances (PFAS)and risk of various allergies in adolescents. The Tromsø study Fit Futures in Northern Norway 

      Averina, Maria; Brox, Jan; Huber, Sandra; Furberg, Anne-Sofie; Sørensen, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      <b>Background:</b> Exposure to environmental pollutants may contribute to the development of asthma and other allergies. The aim of this study was to investigate possible associations between asthma and other allergies with exposure to perfluoroalkyl substances (PFASs) in adolescents from the Arctic region of Norway.<br><b> Methods</b> The Tromsø study Fit Futures 1 (TFF1) and 3-year follow-up Fit ...
    • Social network analysis of Staphylococcus aureus carriage in a general youth population 

      Stensen, Dina Benedicte Berg; Cañadas, Rafael A. Nozal; Småbrekke, Lars; Olsen, Karina; Nielsen, Christopher Sivert; Svendsen, Kristian; Hanssen, Anne Merethe; Ericson, Johanna U; Simonsen, Gunnar Skov; Bongo, Lars Ailo; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-31)
      Objectives Staphylococcus aureus carriage increases infection risk. We used social network analysis to evaluate whether contacts have the same S. aureus genotype indicating direct transmission, or whether contagiousness is an indirect effect of contacts sharing the same lifestyle or characteristics. Methods The Fit Futures 1 study collected data on social contact among 1038 high school students. ...
    • Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromso Staph and Skin Study 

      Olsen, Karina; Falch, Birgit Margrethe; Danielsen, Kjersti; Johannessen, Mona; Sollid, Johanna U Ericson; Thune, Inger; Grimnes, Guri; Jorde, Rolf; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ...
    • Staphylococcus aureus nasal carriage is associated with serum 25-hydroxyvitamin D levels, gender and smoking status. The Tromsø Staph and Skin Study 

      Olsen, Karina; Falch, Birgit Margrethe; Danielsen, Kjersti; Johannessen, Mona; Sollid, Johanna U Ericson; Thune, Inger; Grimnes, Guri; Jorde, Rolf; Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Vitamin D induces the expression of antimicrobial peptides with activity against Staphylococcus aureus. Thus, we studied the association between serum 25-hydroxyvitamin D (25(OH)D) and S. aureus nasal colonization and carriage. Nasal swabs, blood samples and clinical data from 2,115 women and 1,674 men, aged 30–87 years, were collected in the Tromsø Staph and Skin Study 2007–08, as part of the ...
    • Tracking of overweight and obesity from early childhood to adolescence in a population-based cohort – the Tromsø Study, Fit Futures 

      Evensen, Elin Kristin; Wilsgaard, Tom; Furberg, Anne-Sofie; Skeie, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-10)
      BACKGROUND Obesity is a serious childhood health problem today. Studies have shown that overweight and obesity tend to be stable (track) from birth, through childhood and adolescence, to adulthood. However, existing studies are heterogeneous; there is still no consensus on the strength of the association between high birth weight or high body mass index (BMI) early in life and overweight and ...
    • The Tromsø Study: Fit Futures: a study of Norwegian adolescents' lifestyle and bone health 

      Winther, Anne; Dennison, Elaine; Ahmed, Luai Awad; Furberg, Anne-Sofie; Grimnes, Guri; Jorde, Rolf; Gjesdal, Clara Gram; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-04)
      Summary: Bone mass achievement predicts later fracture risk. This population-based study describes bone mineral density levels (BMD) and associated factors in Norwegian adolescents. Compared with international reference ranges, BMD levels appear higher and physical activity levels are positively associated with BMD. <p>Purpose: Norway has one of the highest reported incidences of osteoporotic ...
    • Two-year changes in sleep duration are associated with changes in psychological distress in adolescent girls and boys: the fit futures study 

      Linkas, Jonas; Ahmed, Luai Awad; Csifcsak, Gabor; Emaus, Nina; Furberg, Anne-Sofie; Pettersen, Gunn; Rognmo, Kamilla; Christoffersen, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-21)
      <p><i>Objective -</i> Studies indicate an inverse association between sleep duration and psychological distress. We aimed to explore associations between changes in sleep duration and changes in psychological distress in girls and boys. <p><i>Methods -</i> The Fit Futures Study is a broad adolescent study providing data from 373 girls and 294 boys aged 15–18 years collected in 2010/2011 (FF1) and ...