• Does the frequency and intensity of physical activity in adolescence have an impact on bone? The Tromsø Study, Fit Futures 

      Christoffersen, Tore; Winther, Anne; Nilsen, Ole-Andreas; Ahmed, Luai Awad; Furberg, Anne-Sofie; Grimnes, Guri; Dennison, Elaine; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-10)
      Background: Optimization of the genetic potential for bone accrual in early life may prevent future fractures. Possible modification factors include lifestyle factors such as nutrition and physical activity. Measured levels of bone mineral density (BMD) and bone mass content (BMC) are indicators of bone strength, and are correlated with fracture risk. This study explored the impact of self-reported ...
    • Driftsrapport 2018 - Norsk overvåkingssystem for antibiotikaresistens hos mikrober NORM 

      Simonsen, Gunnar Skov; Furberg, Anne-Sofie (Research report; Forskningsrapport, 2019)
      Driftsrapporten er en standardisert rapport som gir grunnlag for en samlet oversikt over driften av helseregistrene Folkehelseinstituttet er dataansvarlig og databehandler for. Driftsrapporten brukes også blant annet til å oppfylle enkelte av helseregistrenes forskriftsfestede meldeplikt til Datatilsynet.
    • Early menarche and other endocrine disrupting effects of per- and polyfluoroalkyl substances (PFAS) in adolescents from Northern Norway. The Fit Futures study 

      Averina, Maria; Huber, Sandra; Almås, Bjørg; Brox, Jan; Jacobsen, Bjarne K.; Furberg, Anne-Sofie; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-19)
      Background: Per- and polyfluoroalkyl substances (PFAS) comprise a large group of chemicals that are ubiquitous in the environment and include recognized persistent organic pollutants. The aim of this cross-sectional study was to investigate possible endocrine disrupting effects of different PFAS in adolescents. <p> <p>Methods: Serum concentrations of PFAS, thyroid, parathyroid and steroid hormones ...
    • Early sexual behaviour and Chlamydia trachomatis infection - a population based cross-sectional study on gender differences among adolescents in Norway. 

      Gravningen, Kirsten Midttun; Furberg, Anne-Sofie; Simonsen, Gunnar Skov; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Early sexual behaviour has been shown to differ significantly between genders, but few studies have addressed this topic to explain the commonly observed differences in chlamydia rates between adolescent girls and boys. Our study aimed to determine chlamydia prevalence in adolescents aged 15–20 years in a high-incidence area in Norway, and to identify gender-specific early sexual behaviours associated ...
    • Effect of Vitamin D Supplementation on Psoriasis Severity in Patients With Lower-Range Serum 25-Hydroxyvitamin D Levels A Randomized Clinical Trial 

      Jenssen, Marita; Furberg, Anne-Sofie; Jorde, Rolf; Wilsgaard, Tom; Danielsen, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-29)
      Importance - Topical vitamin D analogues are routine treatment for psoriasis, but the effect of oral supplementation has not been established.<p> <p>Objective - To examine the effect of vitamin D supplementation on psoriasis severity throughout the winter.<p> <p>Design, Setting, and Participants - This randomized, double-blind placebo-controlled clinical trial with 2 parallel groups was performed ...
    • Elevated odds of metabolic syndrome in psoriasis: A population-based study of age and sex differences 

      Danielsen, Kjersti; Wilsgaard, Tom; Olsen, Anne Olaug; Eggen, Anne Elise; Olsen, Karina; Cassano, P. A.; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-07-24)
      Background Questions remain concerning to what extent age and sex may modify the suggested association between psoriasis and the metabolic syndrome in the general population. Objectives To investigate the association between psoriasis and the metabolic syndrome within a large population-based cohort by age and sex.<p> <p>Methods A cross-sectional study including 10 521 participants aged 30–79 ...
    • Environmental factors, metabolic profile, hormones and breast and endometrial cancer risk 

      Furberg, Anne-Sofie (Doctoral thesis; Doktorgradsavhandling, 2004)
      Breast cancer is the leading cancer among women in the Western world. In Norway, 2,503 cases of female breast cancer were diagnosed in 2000, which corresponds to an age-adjusted incidence rate of 72.1 per 100,000 women per year (1). The risk of breast cancer increases with age from puberty, doubling about every 10 years until the menopause, when the rate of increase slows dramatically and a ...
    • Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines 

      Jensen, V. Vorobieva S.; Furberg, Anne-Sofie; Slotved, Hans-Christian; Bazhukova, Tatiana; Haldorsen, Bjørg; Caugant, Dominique A.; Sundsfjord, Arnfinn; Valentiner-Branth, Palle; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-15)
      <p><i>Background - </i>The 13-valent Pneumococcal Conjugate Vaccine (PCV-13) was introduced in the National Immunization Programme (NIP) schedule in Russia in March 2014. Previously, the 7-valent Pneumococcal Conjugate Vaccine (PCV-7) was marketed in Russia in 2009 but has never been offered for mass vaccination. A carriage study was performed among children in Arkhangelsk in 2006. The objective was ...
    • Evaluation of the One Health-Ness of 20 Years of Antimicrobial Resistance Surveillance in Norway 

      Norström, Madelaine; Simonsen, Gunnar Skov; Slettemeås, Jannice Schau; Furberg, Anne-Sofie; Urdahl, Anne Margrete (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-21)
      We evaluated the One Health-ness (OH-ness) of the surveillance system for antimicrobial resistance (AMR) in Norway by using the recently developed “Evaluation tool for One Health epidemiological surveillance capacities and capabilities” (OH–EpiCap tool). First, we defined the Norwegian AMR surveillance system that we would evaluate. The tool was applied by a group of stakeholders (key persons in the ...
    • Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway 

      Mohus, Randi Marie; Gustad, Lise Tuset; Furberg, Anne-Sofie; Moen, Martine Kjølberg; Liyanarachi, Kristin Vardheim; Askim, Åsa Susanne; Åsberg, Signe Elisabeth; DeWan, Andrew T.; Rogne, Tormod; Simonsen, Gunnar Skov; Nilsen, Tom Ivar Lund; Åsvold, Bjørn Olav; Damås, Jan Kristian; Solligård, Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-19)
      Previous studies indicate sex differences in incidence and severity of bloodstream infections (BSI). We examined the effect of sex on risk of BSI, BSI mortality, and BSI caused by the most common infecting bacteria. Using causal mediation analyses, we assessed if this effect is mediated by health behaviours (smoking, alcohol consumption), education, cardiovascular risk factors (systolic blood pressure, ...
    • Exposure to perfluoroalkyl substances (PFAS) and dyslipidemia, hypertension and obesity in adolescents : the Fit Futures study 

      Averina, Maria; Brox, Jan; Huber, Sandra; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-15)
      Background - Prevalence of obesity, hypertension and dyslipidemia has been increasing in children and adolescents worldwide. Exposure to environmental pollutants may contribute to this development. Our aim was to study associations between perfluoroalkyl substances (PFAS) and dyslipidemia, hypertension and obesity in a population-based sample of adolescents. <p> <p>Methods - Serum PFAS concentrations ...
    • Factors associated with Chlamydia trachomatis testing in a high school based screening and previously in clinical practice: a cross-sectional study 

      Gravningen, Kirsten Midttun; Simonsen, Gunnar Skov; Furberg, Anne-Sofie; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      High school based chlamydia screening has been shown to increase uptake and detect hidden infections among sexually active adolescents. Our study aimed to: i) examine the proportions of 15–20 year-olds tested in a high school based screening and previously in clinical practice, ii) determine chlamydia prevalence according to testing pattern, and iii) examine factors associated with testing in the ...
    • Fracture incidence rates in Norwegian children, The Tromsø Study, Fit Futures 

      Christoffersen, Tore; Ahmed, Luai Awad; Winther, Anne; Nilsen, Ole-Andreas; Furberg, Anne-Sofie; Grimnes, Guri; Dennison, Elaine; Center, Jacqueline R; Eisman, John A.; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-08)
      Summary: <br> This study describes childhood fracture rates in Norway, a country known for high fracture rates in the adult population. Fracture rates correspond with other reports from Scandinavia, although with a slightly higher proportion in girls. Indications of increased vulnerability during stages of puberty require further exploration. <p>Introduction: Fractures are common injuries during ...
    • Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal women. 

      Flote, Vidar Gordon; Furberg, Anne-Sofie; McTiernan, Anne; Frydenberg, Hanne; Ursin, Giske; Iversen, Anita; Lofterød, Trygve; Ellison, Peter T.; Wist, Erik; Egeland, Thore; Wilsgaard, Tom; Makar, Karen W; Chang-Claude, Jenny; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-19)
    • Genetic Polymorphism CYP17 rs2486758 and Metabolic Risk Factors Predict Daily Salivary 17 beta-Estradiol Concentration in Healthy Premenopausal Norwegian Women. The EBBA-I Study 

      Iversen, Anita; Thune, Inger; McTiernan, Anne; Makar, Karen W; Wilsgaard, Tom; Ellison, Peter T.; Jasienska, Grazyna; Flote, Vidar Gordon; Poole, Elizabeth M; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-03-14)
      Context: The relationship between low-penetrance genes, metabolic risk factors, and levels of endogenous 17β-estradiol and progesterone, which play a role in breast cancer risk, remains unclear. <br>Objective: The aim of this study was to determine whether common polymorphisms in CYP17, in combination with metabolic risk factors (individually or clustered), alter salivary concentrations of free ...
    • How Is Adolescent Bone Mass and Density Influenced by Early Life Body Size and Growth? The Tromsø Study: Fit Futures—A Longitudinal Cohort Study From Norway 

      Evensen, Elin; Skeie, Guri; Wilsgaard, Tom; Christoffersen, Tore; Dennison, Elaine; Furberg, Anne-Sofie; Grimnes, Guri; Winther, Anne; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-30)
      The effect of birth weight and childhood body mass index (BMI) on adolescents’ bone parameters is not established. The aim of this longitudinal, population‐based study was to investigate the association of birth weight, childhood BMI, and growth, with adolescent bone mass and bone density in a sample of 633 adolescents (48% girls) from The Tromsø Study: Fit Futures. This population‐based cohort study ...
    • The influence of birth weight and length on bone mineral density and content in adolescence: The Tromsø Study, Fit Futures 

      Christoffersen, Tore; Ahmed, Luai A.; Daltveit, Anne Kjersti; Dennison, Elaine; Evensen, Elin; Furberg, Anne-Sofie; Gracia-Marco, Luis; Grimnes, Guri; Nilsen, Ole-Andreas; Schei, Berit; Tell, Grethe S.; Vlachopoulous, Dimitris; Winther, Anne; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-02)
      <p><i>Summary</i> The influence of birth weight and length on bone mineral parameters in adolescence is unclear. We found a positive association between birth size and bone mineral content, attenuated by lifestyle factors. This highlights the impact of environmental stimuli and lifestyle during growth.</p> <p><i>Purpose</i> The influence of birth weight and length on bone mineral density and ...
    • The influence of snuff and smoking on bone accretion in late adolescence. The Tromsø study, Fit Futures 

      Nilsen, Ole-Andreas; Emaus, Nina; Christoffersen, Tore; Winther, Anne; Evensen, Elin; Thrane, Gyrd; Furberg, Anne-Sofie; Grimnes, Guri; Ahmed, Luai A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-27)
      Summary - Areal bone mineral density (aBMD) predicts future fracture risk. This study explores associations between use of tobacco and bone accretion in Norwegian adolescents. Our results indicate that use of snuff is negatively associated with accretion of aBMD in adolescence and may be a signal of increased future fracture risk.<p> <p>Purpose - Bone mineral accrual in childhood and adolescence ...
    • Is change in mental distress among adolescents predicted by sedentary behavior or screen time? Results from the longitudinal population study The Tromsø Study: Fit Futures 

      Opdal, Ida Marie; Morseth, Bente; Handegård, Bjørn Helge; Lillevoll, Kjersti; Nilsen, Wendy; Nielsen, Christopher Sivert; Furberg, Anne-Sofie; Rosenbaum, Simon; Rognmo, Kamilla (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-12)
      <i>Objective</i> - There is growing interest in the relationship between sedentary behaviour and mental distress among adolescents, but the majority of studies to date have relied on self-reported measures with poor validity. Consequently, current knowledge may be affected by various biases. The aim of this study was to investigate the cross-sectional and longitudinal association between (1) objectively ...
    • Leisure time computer use and adolescent bone health - findings from the Tromsø Study, Fit Futures: a cross sectional study 

      Winther, Anne; Ahmed, Luai Awad; Furberg, Anne-Sofie; Grimnes, Guri; Jorde, Rolf; Nilsen, Ole-Andreas; Dennison, Elaine; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-20)
      <p>Objectives: Low levels of physical activity may have considerable negative effects on bone health in adolescence, and increasing screen time in place of sporting activity during growth is worrying. This study explored the associations between self-reported screen time at weekends and bone mineral density (BMD). <p>Design: In 2010/2011, 1038 (93%) of the region’s first-year upper-secondary ...