Now showing items 41-60 of 108

    • The hazards of death by smoking in middle-aged women 

      Gram, Inger Torhild; Sandin, Sven; Braaten, Tonje; Lund, Eiliv; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Recent studies have found that the risk of death continues to increase among female smokers, as compared with women who have never smoked. We wanted to examine the effect of smoking on all-cause and causespecific mortality and calculate the corresponding population attributable fraction (PAF) of mortality in the Norwegian women and cancer study; a nationally representative prospective cohort ...
    • Heterogeneity of Associations between Total and Types of Fish Intake and the Incidence of Type 2 Diabetes: Federated Meta-Analysis of 28 Prospective Studies Including 956,122 Participants 

      Pastorino, Silvia; Bishop, Tom; Sharp, Stephen J.; Pearce, Matthew; Akbaraly, Tasnime; Barbieri, Natalia B.; Bes-Rastrollo, Maira; Beulens, Joline W.J.; Chen, Zhengming; Du, Huaidong; Duncan, Bruce B.; Goto, Atsushi; Härkänen, Tommi; Hashemian, Maryam; Kromhout, Daan; Järvinen, Ritva; Kivimaki, Mika; Knekt, Paul; Lin, Xu; Lund, Eiliv; Magliano, Dianna; Malekzadeh, Reza; Martínez-González, Miguel Ángel; O’donoghue, Gráinne; O’gorman, Donal; Poustchi, Hossein; Rylander, Charlotta; Sawada, Norie; Shaw, Jonathan E.; Schmidt, Maria; Soedamah-Muthu, Sabita S.; Sun, Liang; Wen, Wanqing; Wolk, Alicja; Shu, Xiao-Ou; Zheng, Wei; Wareham, Nicholas J.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-07)
      The association between fish consumption and new-onset type 2 diabetes is inconsistent and differs according to geographical location. We examined the association between the total and types of fish consumption and type 2 diabetes using individual participant data from 28 prospective cohort studies from the Americas (6), Europe (15), the Western Pacific (6), and the Eastern Mediterranean (1) comprising ...
    • High coffee consumption and different brewing methods in relation to postmenopausal endometrial cancer risk in the Norwegian women and cancer study: A population-based prospective study 

      Gavrilyuk, Oxana; Braaten, Tonje; Skeie, Guri; Weiderpass, Elisabete; Dumeaux, Vanessa; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      <i>Background</i>: Coffee and its compounds have been proposed to inhibit endometrial carcinogenesis. Studies in the Norwegian population can be especially interesting due to the high coffee consumption and increasing incidence of endometrial cancer in the country.<p> <p><i>Methods</i>: A total of 97 926 postmenopausal Norwegian women from the population-based prospective Norwegian Women and ...
    • Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer Postgenome Cohort : a cross-sectional analysis 

      Waaseth, Marit; Bakken, Kjersti; Dumeaux, Vanessa; Olsen, Karina Standahl; Rylander, Charlotta; Figenschaug, Yngve; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-14)
      Background: Hormone replacement therapy use (HRT) is associated with increased breast cancer risk. Our primary objective was to explore hormone levels in plasma according to HRT use, body mass index (BMI) and menopausal status. A secondary objective was to validate self-reported questionnaire information on menstruation and HRT use in the Norwegian Women and Cancer postgenome cohort (NOWAC). Methods: ...
    • Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts 

      Fasanelli, Francesca; Baglietto, Laura; Ponzi, Erica; Guida, Florence; Campanella, Gianluca; Johansson, Mattias; Grankvist, Kjell; Johansson, Mikael; Assumma, Manuela Bianca; Naccarati, Alessio; Chadeau-Hyam, Marc; Ala, Ugo; Faltus, Christian; Kaaks, Rudolf; Risch, Angela; De Stavola, Bianca; Hodge, Allison; Giles, Graham G.; Southey, Melissa C.; Relton, Caroline L.; Haycock, Philip C.; Lund, Eiliv; Polidoro, Silvia; Sandanger, Torkjel M; Severi, Gianluca; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-15)
      DNA hypomethylation in certain genes is associated with tobacco exposure but it is unknown whether these methylation changes translate into increased lung cancer risk. In an epigenome-wide study of DNA from pre-diagnostic blood samples from 132 case–control pairs in the NOWAC cohort, we observe that the most significant associations with lung cancer risk are for cg05575921 in AHRR (OR for 1 s.d.=0.37, ...
    • The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk 

      Campa, D; Lund, Eiliv; Husing, A; McKay, JD; Sinilnikova, OM; Vogel, U; Tjonneland, A; Overvad, K; Stegger, J; Clavel-Chapelon, F; Chabbert-Buffet, N; Fagherazzi, G; Trichopoulou, A; Zylis, D; Oustoglou, E; Rohrmann, S; Teucher, B; Fisher, E; Boeing, H; Masala, G; Krogh, V; Sacerdote, C; Panico, S; Tumino, R; Onland-Moret, NC; van Gils, CH; Bueno-de-Mesquita, H. Bas; Chirlaque, MD; Sala, Núria; Quiros, JR; Ardanaz, E; Amiano, P; Molina-Montes, E; Hallmans, G; Lenner, P; Travis, R; Key, TJ; Wareham, N; Khaw, KT; Rinaldi, S; Slimani, N; Chajes, V; Siddiq, A; Riboli, E; Kaaks, R; Canzian, F (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    • Kvik: three-tier data exploration tools for flexible analysis of genomic data in epidemiological studies 

      Fjukstad, Bjørn; Olsen, Karina Standahl; Jareid, Mie; Lund, Eiliv; Bongo, Lars Ailo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-30)
      Kvik is an open-source system that we developed for explorative analysis of functional genomics data from large epidemiological studies. Creating such studies requires a significant amount of time and resources. It is therefore usual to reuse the data from one study for several research projects. Often each project requires implementing new analysis code, integration with specific knowledge bases, ...
    • Kvik: three-tier data exploration tools for flexible analysis of genomic data in epidemiological studies [version 1; peer review: 2 approved with reservations] 

      Fjukstad, Bjørn; Olsen, Karina Standahl; Jareid, Mie; Lund, Eiliv; Bongo, Lars Ailo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-30)
      Kvik is an open-source system that we developed for explorative analysis of functional genomics data from large epidemiological studies. Creating such studies requires a significant amount of time and resources. It is therefore usual to reuse the data from one study for several research projects. Often each project requires implementing new analysis code, integration with specific knowledge bases, ...
    • Levonorgestrel-releasing intrauterine system use is associated with a decreased risk of ovarian and endometrial cancer, without increased risk of breast cancer. Results from the NOWAC Study 

      Jareid, Mie; Thalabard, Jean-Christophe; Aarflot, Morten; Bøvelstad, Hege Marie; Lund, Eiliv; Braaten, Tonje (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-02)
      <p><i>Objective</i>: Women with ovarian cancer have poor survival rates, which have proven difficult to improve; therefore primary prevention is important. The levonorgestrel-releasing intrauterine system (LNG-IUS) prevents endometrial cancer, and recent studies suggested that it may also prevent ovarian cancer, but with a concurrent increased risk of breast cancer. We compared adjusted risks of ...
    • Lifetime number of years of menstruation as a risk index for postmenopausal endometrial cancer in the Norwegian Women and Cancer Study 

      Gavrilyuk, Oxana; Braaten, Tonje; Weiderpass, Elisabete; Licaj, Idlir; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-21)
      <p><i>Introduction</i>: Lifetime number of years of menstruation (LNYM) reflects a woman's cumulative exposure to endogenous estrogen and can be used as a measure of the combined effect of reproductive factors related to endometrial cancer (EC) risk.</p> <p><i>Material and methods</i>: We aimed to study the association between LNYM and EC risk among postmenopausal women and calculate the population ...
    • Lifetime sunburn trajectories and associated risks of cutaneous melanoma and squamous cell carcinoma among a cohort of Norwegian women 

      Lergenmuller, Simon; Rueegg, Corina Silvia; Perrier, Flavie; Robsahm, Trude Eid; Green, Adele C.; Lund, Eiliv; Ghiasvand, Reza; Veierød, Marit Bragelien (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-05)
      Importance - To our knowledge, no study has prospectively investigated sunburn patterns over age periods from childhood to adulthood and their associations with skin cancer risk.<p> <p>Objective - To identify lifetime trajectories of sunburns and compare the association between these trajectories and subsequent risk of cutaneous melanoma and squamous cell carcinoma (cSCC).<p> <p>Design, ...
    • Local In Time Statistics for detecting weak gene expression signals in blood – illustrated for prediction of metastases in breast cancer in the NOWAC Post-genome Cohort 

      Holden, Marit; Holden, Lars; Olsen, Karina Standahl; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-10)
      Background: Functional genomics in a processual analysis cover the time-dependent changes in transcriptomics and epigenetics before diagnosis of a disease, reflecting the changes in both life style and disease processes. The aim of this paper is to explore the dynamic, time-dependent mechanisms of the metastatic processes, using blood transcriptomics and including time in a continuous manner. For ...
    • Lung cancers attributable to environmental tobacco smoke and air pollution in non-smokers in different European countries : a prospective study 

      Lund, Eiliv; Vineis, Paolo; Hoek, Gerald; Krzyzanowski, Michal; Vigna-Taglianti, Federica; Veglia, Fabrizio; Airoldi, Luisa; Raaschou-Nielsen, Ole; Clavel-Chapelon, Francoise; Linseisen, Jacob; Boeing, Heiner; Trichopoulou, Antonia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Agudo, Antonio; Martinez, Carmen; Dorronsoro, Miren; Barricarte, Aurelio; Cirera, Lluis; Quiros, J Ramon; Berglund, Gøran; Manjer, Jonas; Forsberg, Bertil; Day, Nicholas E.; Key, Tim J.; Kaaks, Rudolf; Saracci, Rodolfo; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2007-02-15)
      Background: Several countries are discussing new legislation on the ban of smoking in public places, and on the acceptable levels of traffic-related air pollutants. It is therefore useful to estimate the burden of disease associated with indoor and outdoor air pollution. Methods: We have estimated exposure to Environmental Tobacco Smoke (ETS) and to air pollution in never smokers and ex-smokers ...
    • Macronutrient composition of the diet and prospective weight change in participants of the EPIC-PANACEA study 

      Vergnaud, Anne-Claire; Norat, Teresa; Mouw, Traci; Romaguera, Dora; May, Anne M.; Bueno-de-Mesquita, H. Bas; van der A, Daphne; Agudo, Antonio; Wareham, Nicholas; Khaw, Kay-Tee; Romieu, Isabelle; Freisling, Heinz; Slimani, Nadia; Perquier, Florence; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Rodriguez, Laudina; Molina-Montes, Esther; Amiano, Pilar; Barricarte, Aurelio; Chirlaque, Maria-Dolores; Crowe, Francesca L.; Orfanos, Philippos; Naska, Androniki; Trichopoulou, Antonia; Teucher, Birgit; Kaaks, Rudolf; Boeing, Heiner; Buijsse, Brian; Johansson, Ingegerd; Hallmans, Göran; Drake, Isabel; Sonestedt, Emily; Jakobsen, Marianne Uhre; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Skeie, Guri; Braaten, Tonje; Lund, Eiliv; Riboli, Eilo; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25–70 years were recruited in 10 European countries (1992–2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and ...
    • Mediterranean dietary pattern and cancer risk in the EPIC cohort 

      Couto, Elisabeth; Boffetta, Paolo; Lagiou, P; Ferrari, P; Buckland, G; Overvad, K; Dahm, CC; Tjonneland, A; Olsen, A; Clavel-Chapelon, F; Boutron-Ruault, MC; Cottet, V; Trichopoulos, D; Naska, A.; Benetou, V; Kaaks, R; Rohrmann, S; Boeing, H; von Ruesten, A; Panico, S; Pala, V; Vineis, P; Palli, D; Tumino, R; May, A; Peeters, PH; Bueno-de-Mesquita, HB; Buchner, FL; Lund, Eiliv; Skeie, Guri; Engeset, Dagrun; Gonzalez, CA; Navarro, C; Rodriguez, L; Sanchez, MJ; Amiano, P; Barricarte, A; Hallmans, G; Johansson, I; Manjer, J; Wirfart, E; Allen, NE; Crowe, F; Khaw, KT; Wareham, N; Moskal, A; Slimani, N; Jenab, M; Romaguera, D; Mouw, T; Norat, T; Riboli, E; Trichopoulou, A (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-04-05)
      BACKGROUND: Although several studies have investigated the association of the Mediterranean diet with overall mortality or risk of specific cancers, data on overall cancer risk are sparse.<p> <p>METHODS: We examined the association between adherence to Mediterranean dietary pattern and overall cancer risk using data from the European Prospective Investigation Into Cancer and nutrition, a multi-centre ...
    • Mellom hypoteser og tilfeldigheter 

      Lund, Eiliv (Others; Andre, 2017)
      Dette er en personlig, objektiv beskrivelse av grunnlaget for Kvinner og Kreft, utviklingen over tid og samspillet mellom ideer, engasjement og tilfeldigheter. Over ca femti år er det meste forandret fra forskning drevet av nysgjerrighet til forskning som konkurranse. Det springende spørsmål er hva som gir best utbytte i fremtiden? Prosjekter har ofte en meget lang tidshorisont. Politiske og ...
    • Menstrual factors, reproductive history, hormone use, and urothelial carcinoma risk: A prospective study in the EPIC cohort 

      Lujan-Barroso, Leila; Botteri, Edoardo; Caini, Saverio; Ljungberg, Börje; Roswall, Nina; Tjønneland, Anne; Bueno-De-Mesquita, Bas; Gram, Inger Torhild; Tumino, Rosario; Kiemeney, Lambertus A.; Liedberg, Fredrik; Stocks, Tanja; Gunter, Marc; Murphy, Neil; Cervenka, Iris; Fournier, Agnès; Kvaskoff, Marina; Häggström, Christel; Overvad, Kim; Lund, Eiliv; Waaseth, Marit; Fortner, Renée T.; Kühn, Tilman; Menéndez, Virginia; Sánchez, María-José; Santiuste, Carmen; Perez-Cornago, Aurora; Zamora-Ros, Raul; Cross, Amanda J.; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Krogh, Vittorio; Sciannameo, Veronica; Mattiello, Amalia; Panico, Salvatore; van Gils, Carla H.; Onland-Moret, N. Charlotte; Barricarte, Aurelio; Amiano, Pilar; Khaw, Kay-Tee; Boeing, Heiner; Weiderpass, Elisabete; Duell, Eric J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-28)
      <p>Background: Urothelial carcinoma is the predominant (95%) bladder cancer subtype in industrialized nations. Animal and epidemiologic human studies suggest that hormonal factors may influence urothelial carcinoma risk. <p>Methods: We used an analytic cohort of 333,919 women from the European Prospective Investigation into Cancer and Nutrition Cohort. Associations between hormonal factors and ...
    • Milk and risk of colorectal, colon and rectal cancer in the Norwegian Women and Cancer (NOWAC) Cohort Study 

      Bakken, Toril; Braaten, Tonje; Olsen, Anja; Hjartåker, Anette; Lund, Eiliv; Skeie, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-17)
      According to World Cancer Research Fund International/American Institute for Cancer Research, it is ‘probable’ that dairy products decrease the risk of colorectal cancer (CRC). However, meta-analyses restricted to women have not shown associations between milk intake and risk of CRC. The aim of this study was to examine the association between milk intake and risk of CRC, colon cancer and rectal ...
    • Modifiable causes of premature death in middle-age in Western Europe: Results from the EPIC cohort study 

      Muller, David C.; Murphy, Neil; Johansson, Mattias; Ferrari, Pietro; Tsilidis, Konstantinos K.; Boutron-Ruault, Marie-Christine; Clavel, Francoise; Dartois, Laureen; Li, Kuanrong; Kaaks, Rudolf; Weikert, Cornelia; Bergmann, Manuela; Boeing, Heiner; Tjønneland, Anne; Overvad, Kim; Redondo, María-Luisa; Agudo, Antonio; Molina-Portillo, Elena; Altzibar, Jone M.; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nicholas J.; Key, Timothy J.; Travis, Ruth C.; Bamia, Christina; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Verschuren, W.M. Monique; Struijk, Ellen A.; Peeters, Petra H.; Engström, Gunnar; Melander, Olle; Sund, Malin; Weiderpass, Elisabete; Skeie, Guri; Lund, Eiliv; Norat, Teresa; Gunter, Marc; Riboli, Elio; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-14)
      Background<br> Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, hypertension, obesity, physical inactivity, alcohol and poor diet towards risk of premature death.<br> Methods<br> We analysed data from 264,906 European adults from the ...
    • Mr. Clean: A Tool for Tracking and Comparing the Lineage of Scientific Visualization Code 

      Tartari, Giacomo; Tiede, Lars; Holsbø, Einar; Knudsen, Kenneth; Raknes, Inge Alexander; Fjukstad, Bjørn; Mode, Nicolle; Bjørndalen, John Markus; Lund, Eiliv; Bongo, Lars Ailo (Conference object; Konferansebidrag, 2014)