Blar i forfatter "Wareham, Nick"

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    • A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Cross, Amanda J; Abubakar, Mustapha; Jenab, Mazda; Aleksandrova, Krasmira; Boutron-Ruault, Marie-Christine; Dossus, Laure; Racine, Antoine; Kühn, Tilman; Katzke, Verena A.; Tjønneland, Anne; Petersen, Kristina E N; Overvad, Kim; Quiros, J Ramon; Jakszyn, Paula; Molina-Montes, Esther; Dorronsoro, Miren; Huerta, José-Maria; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nick; Travis, Ruth C; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Siersema, Peter D; Peeters, Petra H; Ohlsson, Bodil; Ericson, Ulrika; Palmqvist, Richard; Nyström, Hanna; Weiderpass, Elisabete; Skeie, Guri; Freisling, Heinz; Kong, So Yeon; Tsilidis, Kostas; Muller, David C; Riboli, Eilo; Gunter, Marc J (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-05)
      Background:<br> Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterparts. ...

    • Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study 

      Deschasaux, Mélanie; Huybrechts, Inge; Murphy, Neil; Julia, Chantal; Hercberg, Serge; Srour, Bernard; Kesse-Guyot, Emmanuelle; Latino-Martel, Paule; Biessy, Carine; Casagrande, Corinne; Jenab, Mazda; Ward, Heather; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Kyrø, Cecilie; Olsen, Anja; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Mahamat-Saleh, Yahya; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Schwingshackl, Lukas; Bamia, Christina; Peppa, Eleni; Trichopoulou, Antonia; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Hjartåker, Anette; Rylander, Charlotta; Skeie, Guri; Ramõn Quirõs, Jose; Jakszyn, Paula; Salamanca-Fernández, Elena; Huerta, José María; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Sonestedt, Emily; Huseinovic, Ena; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Ferrari, Pietro; Riboli, Elio; Gunter, Mark J.; Touvier, Mathilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-18)
      <p><i>Background - </i>Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British ...

    • Plasma alkylresorcinols, biomarkers of whole-grain wheat and rye intake, and incidence of colorectal cancer 

      Kyrø, Cecilie; Olsen, Anja; Landberg, Rikard; Skeie, Guri; Loft, Steffen; Åman, Per; Leenders, Max; Dik, Vincent K.; Siersema, Peter D.; Pischon, Tobias; Christensen, Jane; Overvad, Kim; Boutron-Ruault, Marie Christine; Fagherazzi, Guy; Cottet, Vanessa; Kühn, Tilman; Chang-Claude, Jenny; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Trichopoulos, Dimitrios; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H.; Weiderpass, Elisabete; Bakken, Toril; Åsli, Lene Angell; Arguelles, Marcial; Jakszyn, Paula; Sánchez, Maria-Jose; Amiano, Pilar; Huerta, Jose Maria; Barricarte, Aurelio; Ljuslinder, Ingrid; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J; Travis, Ruth C.; Ferrari, Pietro; Freisling, Heinz; Jenab, Mazda; Gunter, Marc J; Murphy, Neil; Riboli, Elio; Tjønneland, Anne; Bueno-de-Mesquita, H. Bas (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-12-07)
      Background<p> <p>Few studies have investigated the association between whole-grain intake and colorectal cancer. Because whole-grain intake estimation might be prone to measurement errors, more objective measures (eg, biomarkers) could assist in investigating such associations.<p> <p>Methods <p>The association between alkylresorcinols, biomarkers of whole-grain rye and wheat intake, and colorectal ...

    • Plasma concentrations of persistent organic pollutants and pancreatic cancer risk 

      Porta, Miquel; Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Agudo, Antoni; Rylander, Charlotta; Nøst, Therese Haugdahl; Donat-Vargas, Carolina; Aune, Dagfinn; Heath, Alicia K; Cirera, Lluís; Goni-Irigoyen, Fernando; Alguacil, Juan; Giménez-Robert, Álex; Tjønneland, Anne; Sund, Malin; Overvad, Kim; Romana Mancini, Francesca; Rebours, Vinciane; Boutron-Ruault, Marie Christine; Kaaks, Rudolf; Schulze, Matthias B.; Trichopoulou, Antonia; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Vermeulen, Roel; Ramón Quirós, J; Rodríguez-Barranco, Miguel; Colorado-Yohar, Sandra M.; Chirlaque, María Dolores; Ardanaz, Eva; Wareham, Nick; Key, Tim; Johansson, Mattias; Murphy, Neil; Ferrari, Pietro; Huybrechts, Inge; Chajes, Veronique; Gonzalez, Carlos Alberto; de Mesquita, Bas Bueno; Gunter, Marc; Vainio, Elisabete Weiderpass; Riboli, Elio; Duell, Eric J; Katzke, Verena; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-14)
      Background: Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts.<p> Methods: We conducted a prospective case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Participants were 513 pancreatic cancer cases and 1020 matched ...

    • Plasma microRNAs as biomarkers of pancreatic cancer risk in a prospective cohort study 

      Duell, Eric J.; Lujan-Barroso, Leila; Sala, Núria; Deitz McElyea, Samantha; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Weiderpass, Elisabete; Busund, Lill-Tove; Moi, Line; Muller, David; Aune, Dagfinn; Naccarati, Alessio; Panico, Salavatore; Tagliabue, Giovanna; Tumino, Rosario; Palli, Domenico; Kaaks, Rudolf; Katzke, Verena A.; Boeing, Heiner; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Trichopoulou, Antonia; Lagiou, Pagona; Kotanidou, Anastasia; Travis, Ruth C.; Wareham, Nick; Khaw, Kay-Tee; Quirõs, Jose Ramõn; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, María Dolores; Ardanaz, Eva; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Rebours, Vinciane; Brennan, Paul; Gunter, Marc; Scelo, Ghislaine; Cote, Greg; Sherman, Stuart; Korc, Murray (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-12)
      Noninvasive biomarkers for early pancreatic ductal adenocarcinoma (PDAC) diagnosis and disease risk stratification are greatly needed. We conducted a nested case-control study within the Prospective Investigation into Cancer and Nutrition (EPIC) cohort to evaluate prediagnostic microRNAs (miRs) as biomarkers of subsequent PDAC risk. A panel of eight miRs (miR-10a, -10b, -21-3p, -21-5p, -30c, -106b, ...

    • Pre-diagnostic copper and zinc biomarkers and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort 

      Stepien, Magdalena; Jenab, Mazda; Freisling, Heinz; Becker, Niels-Peter; Czuban, Magdalena; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Savoye, Isabelle; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Iqbal, Khalid; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Weiderpass, Elisabete; Merino, Susana; Jakszyn, Paula; Sánchez, María-José; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Boden, Stina; van Guelpen, Behany; Wareham, Nick; Khaw, Kay-Tee; Bradbury, Kathryn E.; Cross, Amanda J.; Schomburg, Lutz; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed; Preprint; Manuskript, 2017-07-01)
      Adequate intake of copper and zinc, two essential micronutrients, are important for antioxidant functions. Their imbalance may have implications for development of diseases like colorectal cancer (CRC), where oxidative stress is thought to be etiologically involved. As evidence from prospective epidemiologic studies is lacking, we conducted a case-control study nested within the European Prospective ...

    • Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition 

      Perez-Cornago, Aurora; Appleby, Paul N.; Tipper, Sarah; Key, Timothy J.; Allen, Naomi E.; Nieters, Alexandra; Vermeulen, Roel; Roulland, Sandrine; Casabonne, Delphine; Kaaks, Rudolf; Fortner, Renée T.; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Klinaki, Eleni; Hansen, Louise; Tjønneland, Anne; Bonnet, Fabrice; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Pala, Valeria; Masala, Giovanna; Sacerdote, Carlotta; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete; Dorronsoro, Miren; Quirós, J. Ramón; Barricarte, Aurelio; Gavrila, Diana; Agudo, Antonio; Borgquist, Signe; Rosendahl, Ann H.; Melin, Beatrice; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc; Riboli, Elio; Vineis, Paolo; Travis, Ruth C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-27)
      Insulin-like growth factor (IGF)-I has cancer promoting activities. However, the hypothesis that circulating IGF-I concentration is related to risk of lymphoma overall or its subtypes has not been examined prospectively. IGF-I concentration was measured in pre-diagnostic plasma samples from a nested case–control study of 1,072 cases of lymphoid malignancies and 1,072 individually matched controls ...

    • Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study. 

      Ritte, Rebecca; Tikk, Kaja; Lukanova, Annekatrin; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Dossus, Laure; Fournier, Agnes; Clavel-Chapelon, Françoise; Grote, Verena; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Quirós, José Ramón; Buckland, Genevieve; Molina-Montes, Esther; Chirlaque, María Dolores; Ardanaz, Eva; Amiano, Pilar; Bueno-de-Mesquita, H. Bas; van Gils, Carla H.; Peeters, Petra H M; Wareham, Nick; Khaw, Kay-Tee; Key, Timothy J; Travis, Ruth C.; Weiderpass, Elisabete; Dumeaux, Vanessa; Lund, Eiliv; Sund, Malin; Andersson, Anne; Romieu, Isabelle; Rinaldi, Sabina; Vineis, Paolo; Merritt, Melissa A; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain. Methods Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships of reproductive factors (menarcheal age, time between menarche and first pregnancy, parity, number of children, age at first and last pregnancies, time since last full-term ...

    • Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies 

      Wood, Angela M.; Kaptoge, Stephen; Butterworth, Adam S.; Willeit, Peter; Warnakula, Samantha; Bolton, Thomas; Paige, Ellie; Paul, Dirk S.; Sweeting, Michael; Burgess, Stephen; Bell, Steven; Astle, William; Stevens, David; Koulman, Albert; Selmer, Randi; Verschuren, W.M. Monique; Sato, Shinichi; Njølstad, Inger; Woodward, Mark; Salomaa, Veikko; Nordestgaard, Børge G.; Yeap, Bu B.; Fletcher, Astrid; Melander, Olle; Kuller, Lewis H.; Balkau, Beverley; Marmot, Michael; Koenig, Wolfgang; Casiglia, Edoardo; Cooper, Cyrus; Arndt, Volker; Franco, Oscar H.; Wennberg, Patrik; Gallacher, John; de la Cámara, Agustín Gómez; Völzke, Henry; Dahm, Christina C.; Dale, Caroline E.; Bergmann, Manuela M.; Crespo, Carlos J.; van der Schouw, Yvonne T.; Kaaks, Rudolf; Simons, Leon A.; Lagiou, Pagona; Schoufour, Josje D.; Boer, Jolanda M.A.; Key, Timothy J.; Rodriguez, Beatriz; Moreno-Iribas, Conchi; Davidson, Karina W.; Taylor, James O.; Sacerdote, Carlotta; Wallace, Robert B.; Quiros, J. Ramon; Tumino, Rosario; Blazer, Dan G.; Linneberg, Allan; Daimon, Makoto; Panico, Salvatore; Howard, Barbara; Skeie, Guri; Strandberg, Timo; Weiderpass, Elisabete; Nietert, Paul J.; Psaty, Bruce M.; Kromhout, Daan; Salamanca-Fernández, Elena; Kiechl, Stefan; Krumholz, Harlan M.; Grioni, Sara; Palli, Domenico; Huerta, Jose M.; Price, Jackie; Sundström, Johan; Arriola, Larraitz; Arima, Hisatomi; Travis, Ruth C.; Panagiotakos, Demosthenes B.; Karakatsani, Anna; Trichopoulou, Antonia; Kühn, Tilman; Grobbee, Diederick E.; Barrett-Connor, Elizabeth; van Schoor, Natasja; Boeing, Heiner; Overvad, Kim; Kauhanen, Jussi; Wareham, Nick; Langenberg, Claudia; Forouhi, Nita; Wennberg, Maria; Despres, Jean-Pierre; Cushman, Mary; Cooper, Jackie A.; Rodriguez, Carlos J.; Sakurai, Masaru; Shaw, Jonathan E.; Knuiman, Matthew; Voortman, Trudy; Meisinger, Christa; Tjønneland, Anne; Brenner, Hermann; Palmieri, Luigi; Dallongeville, Jean; Brunner, Eric J.; Assmann, Gerd; Trevisan, Maurizio; Gillum, Richard F.; Ford, Ian; Sattar, Naveed; Lazo, Mariana; Thompson, Simon G.; Ferrari, Pietro; Leon, David A.; Smith, George Davey; Peto, Richard; Jackson, Rod; Banks, Emily; Di Angelantonio, Emanuele; Danesh, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-12)
      <p><i>Background - </i>Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. <p><i>Methods - </i>We did a combined analysis of ...

    • Social Inequalities and Mortality in Europe - Results from a Large Multi-National Cohort 

      Gallo, Valentina; Mackenbach, Johan P.; Ezzati, Majid; Menvielle, Gwenn; Kunst, Anton E.; Rohrmann, Sabine; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Tjønneland, Anne; Dalton, Susanne O.; Overvad, Kim; Redondo, Maria Luisa; Agudo, Antonio; Daponte, Antonio; Arriola, Larraitz; Navarro, Camen; Gurrea, Aurelio Barricarte; Khaw, Kay-Tee; Wareham, Nick; Key, Tim; Naska, Androniki; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Masala, Giovanna; Panico, Salvatore; Contiero, Paolo; Tumino, Rosario; Bueno-de-Mesquita, H. Bas; Siersema, Peter D.; Peeters, Petra P. H.; Zackrisson, Sophia; Almquist, Martin; Eriksson, Sture; Hallmans, Göran; Skeie, Guri; Braaten, Tonje; Lund, Eiliv; Illner, Anne-Kathrin; Mouw, Traci; Riboli, Elio; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Socio-economic inequalities in mortality are observed at the country level in both North America and Europe. The purpose of this work is to investigate the contribution of specific risk factors to social inequalities in cause-specific mortality using a large multi-country cohort of Europeans. A total of 3,456,689 person/years follow-up of the European Prospective Investigation into Cancer and ...

    • Validity of a short questionnaire to assess physical activity in 10 European countries 

      Peters, Tricia; Brage, Søren; Westgate, Kate; Franks, Paul W.; Gradmark, Anna; Diaz, Maria Jose Tormo; Huerta, Jose Maria; Bendinelli, Benedetta; Vigl, Matthaeus; Boeing, Heiner; Wendel-Vos, Wanda; Spijkerman, Annemieke; Borch, Kristin Benjaminsen; Valanou, Elisavet; Guillain, Bladine de Lauzon; Clavel-Chapelon, Françoise; Sharp, Stephen; Kerrison, Nicola; Langenberg, Claudia; Arriola, Larraitz; Barricarte, Aurelio; Gonzales, Carlos; Grioni, Sara; Kaaks, Rudolf; Key, Timothy; Khaw, Kay Tee; May, Anne; Nilsson, Peter; Norat, Teresa; Overvad, Kim; Palli, Domenico; Panico, Salvatore; Quirós, José Ramón; Ricceri, Fulvio; Sanchez, Maria-Jose; Slimani, Nadia; Tjonneland, Anne; Tumino, Rosario; Feskens, Edith; Riboli, Elio; Ekelund, Ulf; Wareham, Nick (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-11-17)