Blar i forfatter "Tveita, Torkjel"

Viser treff 21-26 av 26

    • Resistance to ventricular fibrillation predicted by the QRS/QTc - ratio in an intact rat model of hypothermia/rewarming 

      Dietrichs, Erik Sveberg; Selli, Anders Lund; Kondratiev, Timofei; McGlynn, Karen; Smith, Godfrey L; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-04)
      Accidental hypothermia is associated with increased risk for arrhythmias. QRS/QTc is proposed as an ECG-marker, where decreasing values predict hypothermia-induced ventricular arrhythmias. If reliable it should also predict nonappearance of arrhythmias, observed in species like rat that regularly tolerate prolonged hypothermia.<p> <p>A rat model designed for studying cardiovascular function during ...

    • Rewarming From Hypothermic Cardiac Arrest Applying Extracorporeal Life Support: A Systematic Review and Meta-Analysis 

      Bjertnæs, Lars J.; Hindberg, Kristian; Næsheim, Torvind; Suborov, Evgeny V.; Reierth, Eirik; Kirov, Mikhail Y.; Lebedinskii, Konstantin M.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-13)
      <i>Introduction</i>: This systematic review and meta-analysis aims at comparing outcomes of rewarming after accidental hypothermic cardiac arrest (HCA) with cardiopulmonary bypass (CPB) or/and extracorporeal membrane oxygenation (ECMO).<br><br> <i>Material and Methods</i>: Literature searches were limited to references with an abstract in English, French or German. Additionally, we searched ...

    • Rewarming With Closed Thoracic Lavage Following 3-h CPR at 27°C Failed to Reestablish a Perfusing Rhythm 

      Nivfors, Joar O.; Mohyuddin, Rizwan; Schanche, Torstein; Nilsen, Jan Harald; Valkov, Sergei; Kondratiev, Timofei V.; Sieck, Gary C.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-29)
      Introduction: Previously, we showed that the cardiopulmonary resuscitation (CPR) for hypothermic cardiac arrest (HCA) maintained cardiac output (CO) and mean arterial pressure (MAP) to the same reduced level during normothermia (38°C) vs. hypothermia (27°C). In addition, at 27°C, the CPR for 3-h provided global O2 delivery (DO2) to support aerobic metabolism. The present study investigated if rewarming ...

    • Study of the effects of 3 h of continuous cardiopulmonary resuscitation at 27°C on global oxygen transport and organ blood flow 

      Nilsen, Jan Harald; Valkov, Sergei; Mohyuddin, Rizwan; Schanche, Torstein Lindahl; Kondratiev, Timofei V.; Næsheim, Torvind; Sieck, Gary C.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-16)
      <i>Aims</i>: Complete restitution of neurologic function after 6 h of pre-hospital resuscitation and in-hospital rewarming has been reported in accidental hypothermia patients with cardiac arrest (CA). However, the level of restitution of circulatory function during long-lasting hypothermic cardiopulmonary resuscitation (CPR) remains largely unknown. We compared the effects of CPR in replacing ...

    • Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia—Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate 

      Kuzmiszyn, Adrina Kalasho; Selli, Anders Lund; Smaglyukova, Natalia; Kondratiev, Timofei; Fuskevåg, Ole Martin; Lysaa, Roy A; Ravna, Aina Westrheim; Tveita, Torkjel; Sager, Georg; Dietrichs, Erik Sveberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      <p><b>Introduction:</b> Rewarming from accidental hypothermia is often complicated by hypothermia-induced cardiovascular dysfunction, which could lead to shock. Current guidelines do not recommend any pharmacological treatment at core temperatures below 30°C, due to lack of knowledge. However, previous in vivo studies have shown promising results when using phosphodiesterase 3 (PDE3) inhibitors, ...

    • Treatment of cardiovascular dysfunction with PDE5-inhibitors - temperature dependent effects on transport and metabolism of cAMP and cGMP 

      Selli, Anders Lund; Kuzmiszyn, Adrina Kalasho; Smaglyukova, Natalia; Kondratiev, Timofei V.; Fuskevåg, Ole Martin; Lyså, Roy Andre; Ravna, Aina Westrheim; Tveita, Torkjel; Sager, Georg; Dietrichs, Erik Sveberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-30)
      <i>Introduction</i>: Cardiovascular dysfunction is a potentially lethal complication of hypothermia. Due to a knowledge gap, pharmacological interventions are not recommended at core temperatures below 30°C. Yet, further cooling is induced in surgical procedures and survival of accidental hypothermia is reported after rewarming from below 15°C, advocating a need for evidence-based treatment guidelines. ...