Blar i forfatter "Rinaldi, Sabina"

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    • Dietary patterns related to biological mechanisms and survival after breast cancer diagnosis: results from a cohort study 

      Castro-Espin, Carlota; Bonet, Catalina; Crous-Bou, Marta; Katzke, Verena; Le Cornet, Charlotte; Jannasch, Franziska; Schulze, Matthias B.; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Antoniussen, Christian S.; Sánchez, Maria Jose; Amiano, Pilar; Chirlaque, María Dolores; Guevara, Marcela; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; De Magistris, Maria Santucci; Sund, Malin; Bodén, Stina; Jensen, Torill; Olsen, Karina Standahl; Skeie, Guri; Gunter, Marc J.; Rinaldi, Sabina; Gonzalez-Gil, Esther M.; Weiderpass, Elisabete; Christakoudi, Sofia; Heath, Alicia K.; Dossus, Laure; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-03)
      Background - Inflammatory, insulin and oestrogenic pathways have been linked to breast cancer (BC). We aimed to examine the relationship between pre-diagnostic dietary patterns related to these mechanisms and BC survival.<p> <p>Methods - The diabetes risk reduction diet (DRRD), inflammatory score of diet (ISD) and oestrogen-related dietary pattern (ERDP) were calculated using dietary data from ...

    • Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: a Prospective Study and Meta-Analysis 

      Mori, Nagisa; Keski-Rahkonen, Pekka; Gicquiau, Audrey; Rinaldi, Sabina; Dimou, Niki; Harlid, Sophia; Harbs, Justin; Van Guelpen, Bethany; Aune, Dagfinn; Cross, Amanda J.; Tsilidis, Konstantinos K.; Severi, Gianluca; Kvaskoff, Marina; Fournier, Agnès; Kaaks, Rudolf; Fortner, Renée Turzanski; Schulze, Matthias B.; Jakszyn, Paula; Sánchez, Maria-José; Colorado-Yohar, Sandra M.; Ardanaz, Eva; Travis, Ruth; Watts, Eleanor L.; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Buenode-Mesquita, bas; Gram, Inger Torhild; Waaseth, Marit; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-28)
      Background - Observational studies have consistently reported that postmenopausal hormone therapy use is associated with lower colon cancer risk, but epidemiologic studies examining the associations between circulating concentrations of endogenous estrogens and colorectal cancer have reported inconsistent results.<p> <p>Methods - We investigated the associations between circulating concentrations ...

    • Exogenous hormone use and cutaneous melanoma risk in women: The European Prospective Investigation into Cancer and Nutrition 

      Cervenka, Iris; Al Rahmoun, Marie; Mahamat-Saleh, Yahya; Fournier, Agnès; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Caini, Saverio; Palli, Domenico; Ghiasvand, Reza; Veierød, Marit Bragelien; Botteri, Edoardo; Tjønneland, Anne; Olsen, Anja; Fortner, Renée T.; Kaaks, Rudolf; Schulze, Matthias B.; Panico, Salvatore; Trichopoulou, Antonia; Dessinioti, Clio; Niforou, Katerina; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Hendrik Bastiaan; Sandanger, Torkjel M; Colorado-Yohar, Sandra; Sánchez, María-José; Gil Majuelo, Leire; Lujan-Barroso, Leila; Ardanaz, Eva; Merino, Susana; Isaksson, Karolin; Butt, Salma; Ljuslinder, Ingrid; Jansson, Malin; Travis, Ruth C.; Khaw, Kay-Tee; Weiderpass, Elisabete; Dossus, Laure; Rinaldi, Sabina; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      Evidence suggests an influence of sex hormones on cutaneous melanoma risk, but epidemiologic findings are conflicting. We examined the associations between use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk in women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a prospective cohort study initiated in 1992 in 10 ...

    • Healthy lifestyle and risk of cancer in the European prospective investigation into cancer and nutrition cohort study 

      McKenzie, Fiona; Biessy, Carine; Ferrari, Pietro; Freisling, Heinz; Rinaldi, Sabina; Chajes, Veronique; Dahm, Christina C; Overvad, Kim; Dossus, Laure; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Bas Bueno-De-Mesquita, H; May, Anne; Peeters, Petra H; Weiderpass, Elisabete; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Ericson, Ulrica; Wirfalt, Elisabet; Travis, Ruth C; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04)
      It has been estimated that at least a third of the most common cancers are related to lifestyle and as such are preventable. Key modifiable lifestyle factors have been individually associated with cancer risk; however, less is known about the combined effects of these factors. This study generated a healthy lifestyle index score (HLIS) to investigate the joint effect of modifiable factors on ...

    • Inflammatory potential of the diet and association with risk of differentiated thyroid cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Dossus, Laure; Shivappa, Nitin; Hébert, James R.; Agudo, Antonio; Tjonneland, Anne; Halkjaer, Jytte; Overvad, Kim; Katzke, Verena A.; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Dragna, Luca; Iannuzzo, Gabriella; Jensen, Torill Miriam Enget; Brustad, Magritt; Skeie, Guri; Zamora-Ros, Raul; Rodriguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, María-Dolores; Ardanaz, Eva; Almquist, Martin; Sonestedt, Emily; Sandström, Maria; Nilsson, Lena Maria; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina; Boutron-Ruault, Marie-Christine; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
      Purpose - Chronic inflammation is thought to initiate or promote differentiated thyroid cancer (DTC) and previous studies have shown that diet can modulate this inflammatory process. We aimed to evaluate the association of several dietary scores reflecting the inflammatory potential of the diet with DTC risk.<p> <p>Methods - Within the EPIC cohort, 450,063 participants were followed during a mean ...

    • Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohort 

      Ose, Jennifer; Fortner, Renée T; Schock, Helena; Peeters, Petra H.; Onland-Moret, N. Charlotte; Bueno-de-Mesquita, H. Bas; Weiderpass, Elisabete; Gram, Inger Torhild; Overvad, Kim; Tjønneland, Anne; Dossus, Laure; Fournier, Agnes; Baglietto, Laura; Trichopoulou, Antonia; Benetou, Vassiliki; Trichopoulos, Dimitrios; Boeing, Heiner; Masala, Giovanna; Krogh, Vittorio; Matiello, Amalia; Tumino, Rosaria; Popovic, Maja; Obón-Santacana, Mireia; Larrañaga, Nerea; Ardanaz, Eva; Sánchez, María-José; Menéndez, Virginia; Chirlaque, María-Dolores; Travis, Ruth C.; Khaw, Kay-Tee; Brändstedt, Jenny; Idahl, Annika; Lundin, Eva; Rinaldi, Sabina; Kuhn, Elisabetta; Romieu, Isabelle; Gunter, Marc J.; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-04)
      Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics ...

    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...

    • Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition 

      Kliemann, Nathalie; Viallon, Vivian; Murphy, Neil; Beeken, Rebecca J.; Rothwell, Joseph A.; Rinaldi, Sabina; Assi, Nada; van Roekel, Eline H.; Schmidt, Julie A.; Borch, Kristin Benjaminsen; Agnoli, Claudia; Rosendahl, Ann H.; Sartor, Hanna; Huerta, José María; Tjønneland, Anne; Halkjær, Jytte; Bueno-de-Mesquita, Bas; Gicquiau, Audrey; Achaintre, David; Aleksandrova, Krasimira; Schulze, Matthias B.; Heath, Alicia K.; Tsilidis, Konstantinos K.; Masala, Giovanna; Panico, Salvatore; Kaaks, Rudolf; Fortner, Renée T.; Van Guelpen, Bethany; Dossus, Laure; Scalbert, Augustin; Keun, Hector C.; Travis, Ruth C.; Jenab, Mazda; Johansson, Mattias; Ferrari, Pietro; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-30)
      Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study.<p> <p>Methods: Targeted mass spectrometry ...

    • Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Kliemann, Nathalie; Ammar, Romain Ould; Biessy, Carine; Gicquiau, Audrey; Katzke, Verena; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Sánchez, Maria-Jose; Crous-Bou, Marta; Pasanisi, Fabrizio; Tin, Sandar Tin; Perez-Cornago, Aurora; Aune, Dagfinn; Christakoudi, Sofia; Heath, Alicia K.; Colorado-Yohar, Sandra M.; Grioni, Sara; Skeie, Guri; Sartor, Hanna; Idahl, Annika; Rylander, Charlotta; May, Anne M.; Weiderpass, Elisabete; Freisling, Heinz; Playdon, Mary C.; Rinaldi, Sabina; Murphy, Neil; Huybrechts, Inge; Dossus, Laure; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
      Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known.<p> <p>Methods: The association of metabolically defined body size phenotypes with endometrial cancer risk was investigated in a nested case–control study (817 cases/ 817 controls) within the European Prospective Investigation ...

    • Multiple miscarriages are associated with the risk of ovarian cancer: results from the European prospective investigation into cancer and nutrition 

      Braem, Marieke G.M.; Onland-Moret, N. Charlotte; Schouten, Leo J; Kruitwagen, Roy F.P.M.; Lukanova, Annekatrin; Allen, Naomi E.; Wark, Petra A.; Tjønneland, Anne; Hansen, Louise; Braüner, Christina Marie; Overvad, Kim; Clavel-Chapelon, Françoise; Chabbert-Buffet, Nathalie; Teucher, Birgit; Floegel, Anna; Boeing, Heiner; Trichopoulou, Antonia; Adarakis, George; Plada, Maria; Rinaldi, Sabina; Fedirko, Veronika; Romieu, Isabelle; Pala, Valeria; Galasso, Rocco; Sacerdote, Carlotta; Palli, Domenico; Tumino, Rosario; Bueno-De-Mesquita, H. Bas; Gram, Inger Torhild; Gavrilyuk, Oxana; Lund, Eiliv; Sanchez, Maria-José; Bonet, Catalina; Chirlaque, María Dolores; Larranaga, Nerea; Gurrea, Aurelio Barricarte; Quirós, José R.; Idahl, Annika; Ohlson, Nina; Lundin, Eva; Jirström, Karin; Butt, Salma; Tsilidis, Konstantinos K.; Khaw, Kay-Tee; Wareham, Nick; Riboli, Elio; Kaaks, Rudolf; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      While the risk of ovarian cancer clearly reduces with each full-term pregnancy, the effect of incomplete pregnancies is unclear. We investigated whether incomplete pregnancies (miscarriages and induced abortions) are associated with risk of epithelial ovarian cancer. This observational study was carried out in female participants of the European Prospective Investigation into Cancer and Nutrition ...

    • A new pipeline for the normalization and pooling of metabolomics data 

      Viallon, Vivian; His, Mathilde; Rinaldi, Sabina; Breeur, Marie; Gicquiau, Audrey; Hémon, Bertrand; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha Linn; Rothwell, Joseph A.; Lecuyer, Lucie; Severi, Gianluca; Kaaks, Rudolf; Johnson, Theron; Schulze, Matthias B.; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosaria; Ricceri, Fulvio; Monique Verschuren, Verschuren; Engelfriet, Peter; Onland-Moret, Charlotte; Vermeulen, Roel; Nøst, Therese Haugdahl; Urbarova, Ilona; Zamora-Ros, Raul; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Melander, Olle; Ottoson, Filip; Vidman, Linda; Rentoft, Matilda; Schmidt, Julie A.; Travis, Ruth C.; Weiderpass, Elisabete; Johansson, Mattias; Dossus, Laure; Jenab, Mazda; Gunter, Marc; Bermejo, Justo Lorenzo; Scherer, Dominique; Salek, Reza M.; Keski-Rahkonen, Pekka; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-17)

    • Osteoprotegerin and breast cancer risk by hormone receptor subtype: A nested case-control study in the EPIC cohort 

      Fortner, Renée T.; Sarink, Danja; Schock, Helena; Johnson, Theron; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Affret, Aurelie; His, Mathilde; Boutron-Ruault, Marie-Christine; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Palli, Domenico; Sieri, Sabina; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; van Gils, Carla H.; Weiderpass, Elisabete; Lund, Eiliv; Quirós, J. Ramón; Agudo, Antonio; Sánchez, María-José; Chirlaque, María-Dolores; Ardanaz, Eva; Dorronsoro, Miren; Key, Tim; Khaw, Kay-Tee; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-08)
      Background:<br>Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role as the decoy receptor for both the RANK ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Circulating OPG and breast cancer risk has been examined in only one prior study.<br>Methods:<br>A case-control ...

    • Ovarian cancer risk factors by tumor aggressiveness: An analysis from the Ovarian Cancer Cohort Consortium 

      Fortner, Renée T.; Poole, Elizabeth M.; Wentzensen, Nicolas A.; Trabert, Britton; White, Emily; Arslan, Alan A.; Patel, Alpa V.; Setiawan, V. Wendy; Visvanathan, Kala; Weiderpass, Elisabete; Adami, Hans Olov; Black, Amanda; Bernstein, Leslie; Brinton, Louise A.; Buring, Julie; Clendenen, Tess V.; Fournier, Agnès; Fraser, Gary; Gapstur, Susan M.; Gaudet, Mia M.; Giles, Graham G.; Gram, Inger Torhild; Hartge, Patricia; Hoffman-Bolton, Judith; Idahl, Annika; Kaaks, Rudolf; Kirsh, Victoria A.; Knutsen, Synnøve; Koh, Woon-Puay; Lacey, James V.; Lee, I-Min; Lundin, Eva; Merritt, Melissa A.; Milne, Roger L.; Onland-Moret, N. Charlotte; Peters, Ulrike; Poynter, Jenny N.; Rinaldi, Sabina; Robien, Kim; Rohan, Thomas; Sánchez, María-José; Schairer, Catherine; Schouten, Leo J.; Tjønneland, Anne; Townsend, Mary K.; Travis, Ruth C.; Trichopoulou, Antonia; van den Brandt, Piet A.; Vineis, Paolo; Wilkens, Lynne; Wolk, Alicja; Yang, Hannah P.; Zeleniuch-Jacquotte, Anne; Tworoger, Shelley S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-18)

    • Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition 

      Breeur, Marie; Ferrari, Pietro; Dossus, Laure; Jenab, Mazda; Johansson, Mattias; Rinaldi, Sabina; Travis, Ruth C.; His, Mathilde; Key, Tim J.; Schmidt, Julie A.; Overvad, Kim; Tjønneland, Anne; Kyrø, Cecilie; Rothwell, Joseph A.; Laouali, Nasser; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Eichelmann, Fabian; Palli, Domenico; Grioni, Sara; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Bas; Olsen, Karina Standahl; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Quirós, J. Ramón; Bonet, Catalina; Barranco, Miguel Rodríguez; Chirlaque, María-Dolores; Ardanaz, Eva; Sandsveden, Malte; Manjer, Jonas; Vidman, Linda; Rentoft, Matilda; Muller, David; Tsilidis, Kostas; Heath, Alicia K.; Keun, Hector; Adamski, Jerzy; Keski-Rahkonen, Pekka; Scalbert, Augustin; Gunter, Marc J.; Viallon, Vivian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-19)
      Background - Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metabolites potentially associated with multiple cancer types, while also allowing the investigation of cancer type-specific associations.<p> <p>Methods - We analysed targeted metabolomics ...

    • Plasma polyphenols associated with lower high-sensitivity C-reactive protein concentrations: A cross-sectional study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Harms, Laura; Scalbert, Augustin; Zamora-Ros, Raul; Rinaldi, Sabina; Jenab, Mazda; Murphy, Neil; Achaintre, David; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Romana, Mancini; Mahamat-Saleh, Yahya; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katzke, Verena; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Panico, Salvatore; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Hendrik Bastian; Vermeulen, Roel; Weiderpass, Elisabete; Nøst, Therese Haugdahl; Lasheras, Cristina; RodrÍguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Dorronsoro, Miren; Hultdin, Johan; Schmidt, Julie A.; Gunter, Marc; Riboli, Elio; Aleksandrova, Krasimira (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-04)
      Experimental studies have reported on the anti-inflammatory properties of polyphenols. However, results from epidemiological investigations have been inconsistent and especially studies using biomarkers for assessment of polyphenol intake have been scant. We aimed to characterise the association between plasma concentrations of thirty-five polyphenol compounds and low-grade systemic inflammation ...

    • Pre-diagnosis insulin-like growth factor-I and risk of epithelial invasive ovarian cancer by histological subtypes: A collaborative re-analysis from the Ovarian Cancer Cohort Consortium 

      Ose, Jennifer; Schock, Helena; Poole, Elizabeth M.; Lehtinen, Matti; Visvanathan, Kala; Helzlsouer, Kathy; Buring, Julie E.; Lee, I-Min; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Trichopoulou, Antonia; Mattiello, Amalia; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Sánchez, María-José; Idahl, Annika; Travis, Ruth C.; Rinaldi, Sabina; Merritt, Melissa A.; Wentzensen, Nicolas; Tworoger, Shelley S.; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-16)
      Purpose: <br>Biologic evidence suggests that the Insulin-like growth factor (IGF)-family may be involved in the etiology of epithelial invasive ovarian cancer (EOC). However, prospective studies investigating the role of IGF-I in ovarian carcinogenesis have yielded conflicting results.<br> Methods: <br>We pooled and harmonized data from 6 case-control studies nested within the Ovarian Cancer ...

    • Prospective analysis of circulating metabolites and breast cancer in EPIC 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Gicquiau, Audrey; Achaintre, David; Scalbert, Augustin; Ferrari, Pietro; Romieu, Isabelle; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Fournier, Agnès; Rothwell, Joseph A.; Severi, Gianluca; Kühn, Tilman; Fortner, Renée Turzanski; Boeing, Heiner; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; van Gils, Carla H.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Schmidt, Julie A.; Travis, Ruth C.; Riboli, Elio; Tsilidis, Konstantinos K.; Christakoudi, Sofia; Gunter, Mark J.; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <i>Background</i> - Metabolomics is a promising molecular tool to identify novel etiologic pathways leading to cancer. Using a targeted approach, we prospectively investigated the associations between metabolite concentrations in plasma and breast cancer risk.<p> <p><i>Methods</i> - A nested case-control study was established within the European Prospective Investigation into Cancer cohort, which ...

    • Prospective analysis of circulating metabolites and endometrial cancer risk 

      Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros P.; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa A.; Allen, Naomi E.; Fortner, Renée T.; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger Torhild; Rothwell, Joseph A.; Lécuyer, Lucie; Severi, Gianluca; Schulze, Matthias B.; Nøst, Therese Haugdahl; Crous-Bou, Marta; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Schmidt, Julie A.; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia K.; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Travis, Ruth C.; Gunter, Marc J.; Keun, Hector C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Background. Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel metabolic pathways associated with endometrial cancer we performed metabolomic analyses on pre-diagnostic plasma samples from 853 case-control pairs from the European Prospective ...

    • A prospective evaluation of plasma phospholipid fatty acids and breast cancer risk in the EPIC study 

      Chajès, Véronique; Assi, Nada; Biessy, Carine; Ferrari, P.; Rinaldi, Sabina; Slimani, Nadia; Lenoir, GM; Baglietto, L; His, Mathilde; Boutron-Ruault, M.C.; Trichopoulou, A; Lagiou, P.; Katsoulis, M; Kaaks, R.; Kuhn, T.; Panico, S.; Pala, V; Masala, G; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, P.H.; van Gils, Carla; Hjartåker, Anette; Olsen, Karina Standahl; Borgund Barnung, Runa; Barricarte, A; Redondo-Sánchez, Daniel; Menéndez, V; Amiano, P.; Wennberg, Maria; Key, T.; Khaw, K.T.; Merritt, M.A.; Riboli, E.; Gunter, M.J.; Romieu, I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-18)
      <p><i>Background</i>: Intakes of specific fatty acids have been postulated to impact breast cancer risk but epidemiological data based on dietary questionnaires remain conflicting.</p> <p><i>Materials and methods</i>: We assessed the association between plasma phospholipid fatty acids and breast cancer risk in a case–control study nested within the European Prospective Investigation into Cancer ...

    • Reliability of serum metabolites over a two-year period: A targeted metabolomic approach in fasting and non-fasting samples from EPIC 

      Carayol, Marion; Licaj, Idlir; Achaintre, David; Vineis, Paolo; Key, Timothy J.; Moret, N. Charlotte Onland; Scalbert, Augustin; Rinaldi, Sabina; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-14)
      Objective Although metabolic profiles have been associated with chronic disease risk, lack of temporal stability of metabolite levels could limit their use in epidemiological investigations. The present study aims to evaluate the reliability over a two-year period of 158 metabolites and compare reliability over time in fasting and non-fasting serum samples. <p>Methods Metabolites were measured ...