Blar i forfatter "Paulssen, Ruth H"

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    • Transcriptional profiling of ulcerative colitis in remission 

      Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Paulssen, Ruth H (Journal article; Tidsskriftartikkel, 2019-01-25)
      <p><i>Background - </i>This study addresses whether existing transcriptional profiles can improve and support the current definition of UC in remission apart from the today existing endoscopic, histological and laboratory scoring systems. <p><i>Methods - </i>Mucosal biopsies from treatment-naïve UC patients (<i>n</i> = 14), healthy controls (<i>n</i> = 16), and UC patients in remission (<i>n</i> = ...

    • Transcriptional signatures that define ulcerative colitis in remission 

      Fenton, Christopher Graham; Taman, Hagar; Florholmen, Jon; Sørbye, Sveinung; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-23)
      <i>Background</i> - This study addresses whether existing specific transcriptional profiles can improve and support the current status of the definition of ulcerative colitis (UC) remission apart from the existing endoscopic, histologic, and laboratory scoring systems. For that purpose, a well-stratified UC patient population in remission was compared to active UC and control patients and was ...

    • Transcriptomic Landscape of Treatment-Naïve Ulcerative Colitis 

      Taman, Hagar; Fenton, Christopher Graham; Hensel, Inga Viktoria; Anderssen, Endre; Florholmen, Jon; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-10)
      Background and Aims: Ulcerative colitis [UC] is a chronic inflammatory disease that effects the gastrointestinal tract and is considered one of the most prominent and common forms of inflammatory bowel disease [IBD]. This study aimed to define and describe the entire transcriptomic landscape in a well-stratified, treatment-naïve UC patient population compared ...