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norskBlar i forfatter "Norum, Jan"
Viser treff 21-36 av 36
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Ny medikamentell behandling av brystkreft Adjuvant behandling med trastuzumab ved tidlig stadium av brystkreft - en helseøkonomisk analyse
(Research report; Forskningsrapport, 2006)Denne rapporten er andre del av et oppdrag fra Sosial- og helsedirektoratet og RHF - fagdirektørene med fokus på virkestoffet trastuzumab ved adjuvant behandling av brystkreft. Adjuvant behandling gis i tillegg til hovedbehandlingen (for eksempel kirurgi) for å påvirke eventuelt gjenværende kreftceller hos pasienten. Denne delen av oppdraget vurderer de helseøkonomiske konsekvensene av adjuvant ... -
Pembrolizumab as second-line therapy in non-small cell lung cancer in northern Norway: budget impact and expected gain—a model-based analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-29)1 Norum J, et al . ESMO Open 2017; 2 :e000222. doi:10.1136/esmoopen-2017-000222 Open Access Abstr A ct Background P embrolizumab is a new drug approved in several countries for second-line therapy in non-small cell lung cancer (NSCLC) being programmed cell death ligand (PD-L1) positive. This drug has a high cost, and the cost- effectiveness ratio has been debated. Patients ... -
PET-CT in the-subarctic region of Norway 2010-2013. At the edge of what is possible?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-28)Background It is challenging to obtain a similar access to positron emission tomography/computed tomography (PET-CT) within the whole region served. In the subarctic and arctic region of Norway, significant distances, weather conditions and seasonable darkness have been challenging when the health care provider has aimed for a high quality PET-CT service with similar availability to all inhabitants. ... -
Presentation and course of brain metastases from breast cancer in a paranoid-schizophrenic patient : a case report
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-09-30)Case presentation: This is an unusual case where a 49-year old female patient with known schizophrenia, paranoid type and a history of early-stage breast cancer, which was treated more than 6 years earlier, attempted suicide. Computed tomography and magnetic resonance imaging after this incident revealed the presence of multiple brain metastases as the first symptomatic site of recurrent cancer. ... -
A prospective analysis of false positive events in a National Colon Cancer Surveillance Program
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Quality of obstetric care in the sparsely populated sub-arctic area of Norway 2009-2011
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: It is challenging to obtain high quality obstetric care in a sparsely populated area. In the subarctic region of Norway, significant distances, weather conditions and seasonable darkness have called for a decentralized care model. We aimed to explore the quality of this care. Methods: A retrospective study employing data (2009–11) from the Medical Birth Registry of Norway was initiated. ... -
Regional differences in renal replacement therapy in northern Norway 2000-2012
(Journal article; Tidsskriftartikkel, 2015-02-10)Objectives: Distance from residence location to a centre for renal replacement therapy (RRT) may influence patients’ quality of life and prognosis. Northern Norway constitutes 45% of Norway’s landmass, but has less than 10% of the population. <p>Methods: In this study, we analysed all patients in northern Norway consecutively registered in the Norwegian Renal Registry during 20002012. A total ... -
Sami-speaking municipalities and a control group's access to somatic specialist health care (SHC): a retrospective study on general practitioners' referrals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-03-18)Objectives: The Sami people constitute the indigenous people in northern Norway. The objective of this study was to clarify whether they have a similar supply of somatic specialist health care (SHC) as others.<p> <p>Methods: The referrals from general practitioners (GPs) in the primary health care (PHC) in the administration area of the Sami language law (8 municipalities) were matched with a ... -
Short survival time after palliative whole brain radiotherapy: Can we predict potential overtreatment by use of a nomogram?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-01)Background:<br> Many patients with brain metastases undergoing whole brain radiotherapy (WBRT) have very limited survival. The purpose of this study was to validate a nomogram derived from a large American database and to examine its ability to better predict short survival (cut -off 2 months) than previous models. <br>Material and Methods: <br> This retrospective study included 254 European patients ... -
Should the surgeon or the general practitioner (GP) follow up patients after surgery for colon cancer? A randomized controlled trial protocol focusing on quality of life, cost-effectiveness and serious clinical events
(Journal article; Tidsskriftartikkel, 2008-06-25)Background: All patients who undergo surgery for colon cancer are followed up according to the guidelines of the Norwegian Gastrointestinal Cancer Group (NGICG). These guidelines state that the aims of follow-up after surgery are to perform quality assessment, provide support and improve survival. In Norway, most of these patients are followed up in a hospital setting. We describe a multi-centre ... -
Socioeconomic characteristics and health outcomes in Sami speaking municipalities and a control group in northern Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012-08-20)Objectives. The Sami people constitute an ethnic minority in northern Norway. The objectives of this study were to compare municipalities with a majority of Sami in the population and a control group with regard to socioeconomic factors and health outcome.<p> <p>Methods. Original data from Statistics Norway and Directorate of health on socioeconomic factors (education, unemployment, disability, ... -
Tobacco smoking and cessation and PDL1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-02)<p><i>Background</i>: Programmed death ligand 1 (PD-L1) targeting immunotherapies, as pembrolizumab and nivolumab, have significantly improved outcome in patients with non-small cell lung cancer (NSCLC). Tobacco smoking is the number one risk factor for lung cancer and is linked to 80%–90% of these cancers. Smoking during cancer therapy may influence on radiotherapy and chemotherapy outcome. We aimed ... -
Towards Improved Prognostic Scores Predicting Survival in Patients with Brain Metastases: A Pilot Study of Serum Lactate Dehydrogenase Levels
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Accurate prognostic information is desirable when counselling patients with brain metastases regarding their therapeutic options and life expectancy. Based on previous studies, we selected serum lactate dehydrogenase (LDH) as a promising factor on which we perform a pilot study investigating methodological aspects of biomarker studies in patients with brain metastases, before embarking on large-scale ... -
Treatment of acute myocardial infarction in the sub-arctic region of Norway. Do we offer an equal quality of care?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-26)Patients, relatives, healthcare workers and administrators are concerned about the quality of care offered. We aimed to explore the treatment of acute myocatrdial infarction (AMI) in Northern Norway, compare it with the national figures, and document whether there is an equal quality of care or not. The retrospective study included data on patients' treatment for AMI. The following sources were ... -
An uncommon presentation and course of metastatic malignant melanoma : case report
(Journal article; Tidsskriftartikkel, 2007) -
Wrist malpractice claims in Northern Norway 2005–2014. Lessons to be learned
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-18)Rough weather conditions in the subarctic areas of Norway may influence on the risk of wrist fracture. We implemented data from the Norwegian System of Patient Injury Compensation (NPE). All claims due to wrist surgery, performed at the public hospitals in Northern Norway, during 2005-2014 were analyzed. We employed the ICD-10 classification codes S52.5 (fracture of distal end of radius) and S52.6 ...
