• Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study 

      Tiwari, Sweta; Cerin, Ester; Wilsgaard, Tom; Løvsletten, Ola; Njølstad, Inger; Grimsgaard, Sameline; Hopstock, Laila Arnesdatter; Schirmer, Henrik; Rosengren, Annika; Kristoffersen, Kathrine; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-24)
      Introduction: Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk factors that contribute to other modifiable risk factors, such as hypertension, raised blood cholesterol, ...
    • Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016 

      Albrektsen, Grethe; Wilsgaard, Tom; Heuch, Ivar; Løchen, Maja-Lisa; Thelle, Dag Steinar; Njølstad, Inger; Grimsgaard, Sameline; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-14)
      Background - The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI.<p> <p>Methods and Results - Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained ...
    • Longitudinal and secular trends in total cholesterol levels and impact of lipid-lowering drug use among Norwegian women and men born in 1905–1977 in the population-based Tromsø Study 1979–2016 

      Hopstock, Laila Arnesdatter; Bønaa, Kaare; Eggen, Anne Elise; Grimsgaard, Sameline; Jacobsen, Bjarne K.; Løchen, Maja-Lisa; Mathiesen, Ellisiv B.; Njølstad, Inger; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-21)
      Objectives: <br> Elevated blood cholesterol is a modifiable risk factor for cardiovascular disease. Cholesterol level surveillance is necessary to study population disease burden, consider priorities for prevention and intervention and understand the effect of diet, lifestyle and treatment. Previous studies show a cholesterol decline in recent decades but lack data to follow individuals born ...
    • Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: the Tromsø Study, Fit Futures 

      Aars, Nils Abel; Jacobsen, Bjarne Koster; Morseth, Bente; Emaus, Nina; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-17)
      <p><i>Background - </i>It is not clear how physical activity affects body composition in adolescents. Physical activity levels are often reduced during this period, and the relative proportion of body fat mass and lean mass undergo natural changes in growing adolescents. We aimed to examine whether self-reported physical activity in leisure time at baseline or change in activity during follow-up ...
    • Measuring Physical Activity Using Triaxial Wrist Worn Polar Activity Trackers: A Systematic Review 

      Henriksen, André; Johansson, Jonas; Hartvigsen, Gunnar; Grimsgaard, Sameline; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Collecting objective physical activity data from research participants are increasingly done using consumer-based activity trackers. Several validation studies of Polar devices are conducted to date, but no systematic review of the current level of accuracy for these devices exist. The aim of this study is therefore to investigate the accuracy of current wrist-worn Polar devices that equips a triaxial ...
    • Moderate-to-vigorous physical activity modifies the relationship between sedentary time and sarcopenia: the Tromsø Study 2015–2016 

      Johansson, Jonas; Morseth, Bente; Scott, David; Strand, Bjørn Heine; Hopstock, Laila Arnesdatter; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-01)
      <p>Background: Sarcopenia is an age-related muscle disease primarily characterized by reductions in muscle strength that increases the risk of falls, fractures, cognitive impairment, and mortality. Exercise is currently preferred in prevention and treatment, but it is unknown how different habitual physical activity and sedentary behaviour patterns associate with sarcopenia status. The purpose of ...
    • No additional long-term effect of group vs individual family intervention in the treatment of childhood obesity - A randomised trial 

      Kokkvoll, Ane Sofie; Grimsgaard, Sameline; Flægstad, Trond; Andersen, Lars Bo; Ball, Geoff; Wilsgaard, Tom; Njølstad, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      <i>Aim</i> - Long‐term evaluations of childhood obesity treatments are needed. We examined changes in weight and cardiometabolic risk 1 year after children completed individual family or group‐based weight management interventions.<p><p> <i>Methods</i> - In 2009‐2010, 6‐ to 12‐year‐old children with overweight or obesity from Finnmark and Troms (Norway) were recruited after media coverage and ...
    • Physical activity levels in adults and elderly from triaxial and uniaxial accelerometry. The Tromsø Study 

      Sagelv, Edvard Hamnvik; Ekelund, Ulf; Pedersen, Sigurd; Brage, Søren; Hansen, Bjørge Hermann; Johansson, Jonas; Grimsgaard, Sameline; Nordström, Anna; Horsch, Alexander; Hopstock, Laila Arnesdatter; Morseth, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-03)
      <i>Introduction</i> - Surveillance of physical activity at the population level increases the knowledge on levels and trends of physical activity, which may support public health initiatives to promote physical activity. Physical activity assessed by accelerometry is challenged by varying data processing procedures, which influences the outcome. We aimed to describe the levels and prevalence estimates ...
    • Polar Vantage and Oura Physical Activity and Sleep Trackers: Validation and Comparison Study 

      Henriksen, André; Grimsgaard, Sameline; Hartvigsen, Gunnar; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-27)
      Background: Consumer-based activity trackers are increasingly used in research, as they have the potential to promote increased physical activity and can be used for estimating physical activity among participants. However, the accuracy of newer consumer-based devices is mostly unknown, and validation studies are needed.<p> <p>Objective: The objective of this study was to compare the Polar Vantage ...
    • Pragmatiske studier – hva er det? 

      Lyngbakken, Magnus Nakrem; Paulsen, Aksel; Sethupathy, Ashwini; Hesselberg, Øyvind; Grimsgaard, Sameline; Hagen, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-11)
      Konseptet pragmatiske studier ble foreslått av Schwartz og Lellouch i 1967 og problematiserte to viktige aspekter ved utprøving av ny behandling, nemlig forståelse og beslutning (1). Tradisjonelle forklarende effektstudier (explanatory trials) har som mål å øke vår forståelse ved å vise om en behandling virker per se, ofte under optimale forhold med nøye utvalgte studiedeltakere og utfallsmål. ...
    • Prevalence of general and abdominal obesity in 2015–2016 and 8-year longitudinal weight and waist circumference changes in adults and elderly: the Tromsø Study 

      Løvsletten, Ola; Jacobsen, Bjarne Koster; Grimsgaard, Sameline; Njølstad, Inger; Wilsgaard, Tom; Løchen, Maja-Lisa; Eggen, Anne Elise; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-05)
      <i>Objectives</i> - To describe the prevalence of general (body mass index (BMI) ≥30 kg/m2) and abdominal (waist circumference women >88 cm, men >102 cm) obesity in Tromsø 7 (2015–2016), and the secular change from Tromsø 6 (2007–2008). Furthermore, to study longitudinal changes in body weight and waist circumference from Tromsø 6 to Tromsø 7.<p> <p><i>Setting</i> - A population study in Tromsø, ...
    • Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016 

      Lundblad, Marie Wasmuth; Jacobsen, Bjarne Koster; Johansson, Jonas; de Lucia Rolfe, Emanuella; Grimsgaard, Sameline; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-17)
      Background. Reference values for visceral adipose tissue (VAT) are needed and it has been advocated that body composition measures depend on both the technique and methods applied, as well as the population of interest. We aimed to develop reference values for VAT in absolute grams (VATg), percent (VAT%), and as a kilogram-per-meters-squared index (VATindex) for women and men, and investigate potential ...
    • Secular and longitudinal trends in body composition: The Tromsø Study, 2001 to 2016 

      Lundblad, Marie Wasmuth; Johansson, Jonas; Jacobsen, Bjarne Koster; Grimsgaard, Sameline; Andersen, Lene Frost; Wilsgaard, Tom; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-14)
      <p><i>Objective - </i>Overweight, defined as excessive fat mass, is a long-standing worldwide public health challenge. Traditional anthropometric measures used to identify overweight and obesity do not assess body composition. The aim of this study was to examine population trends in general and abdominal fat mass during the past two decades. <p><i>Methods - </i>This study included participants ...
    • The seventh survey of the Tromsø Study (Tromsø7) 2015–2016: study design, data collection, attendance, and prevalence of risk factors and disease in a multipurpose population-based health survey 

      Hopstock, Laila Arnesdatter; Grimsgaard, Sameline; Johansen, Heidi; Kanstad, kristin maren; Wilsgaard, Tom; Eggen, Anne Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-04)
      Aims: The Tromsø Study is an ongoing population-based health study in Tromsø, Norway, initiated in 1974. The purpose of the seventh survey (Tromsø7) 2015–2016 was to advance the population risk factor surveillance and to collect new types of data. We present the study design, data collection, attendance, and prevalence of risk factors and disease. Methods: All inhabitants in Tromsø municipality, ...
    • Simple cardiovascular risk stratification by replacing total serum cholesterol with anthropometric measures: The MORGAM prospective cohort project 

      Rosberg, Victoria; Vishram-Nielsen, Julie KK; Kristensen, Anna M. Dyrvig; Pareek, Manan; Sehested, Thomas S.G.; Nilsson, Peter M; Linneberg, Allan; Palmieri, Luigi; Giampaoli, Simona; Donfrancesco, Chiara; Kee, Frank; Mancia, Giuseppe; Cesana, Giancarlo; Veronesi, Giovanni; Grassi, Guido; Kuulasmaa, Kari; Salomaa, Veikko; Palosaari, Tarja; Sans, Susana; Ferrieres, Jean; Dallongeville, Jean; Söderberg, Stefan; Moitry, Marie; Drygas, Wojciech; Tamosiunas, Abdonas; Peters, Annette; Brenner, Hermann; Schöttker, Ben; Grimsgaard, Sameline; Biering-Sørensen, Tor; Olsen, Michael H (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-27)
      To assess whether anthropometric measures (body mass index [BMI], waist-hip ratio [WHR], and estimated fat mass [EFM]) are independently associated with major adverse cardiovascular events (MACE), and to assess their added prognostic value compared with serum total-cholesterol. The study population comprised 109,509 individuals (53% men) from the MORGAM-Project, aged 19–97 years, without established ...
    • Single versus multiple-family intervention in childhood overweight - Finnmark Activity School: A randomised trial 

      Kokkvoll, Ane Sofie; Grimsgaard, Sameline; Ødegård, Rønnaug; Flægstad, Trond; Njølstad, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Succeeding with prolonged usage ofconsumer-based activity trackers in clinicalstudies: a mixed methods approach 

      Henriksen, André; Sand, Anne-Sofie; Deraas, Trygve Sigvart; Grimsgaard, Sameline; Hartvigsen, Gunnar; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-27)
      <i>Background</i> - Lack of physical activity (PA) is a risk factor for death and non-communicable disease. Despite this, more than one fourth of adults worldwide do not follow PA guidelines. As part of a feasibility study to test a complex intervention for increasing PA, we included a consumer-based activity tracker (AT) as a tool to measure PA outcomes and to track heart rate during exercise ...
    • Treatment target achievement after myocardial infarction and ischemic stroke: cardiovascular risk factors, medication use and lifestyle – The Tromsø Study 2015-2016. Secondary prevention in myocardial infarction and stroke 

      Hopstock, Laila Arnesdatter; Morseth, Bente; Cook, Sarah; Eggen, Anne Elise; Grimsgaard, Sameline; Lundblad, Marie Wasmuth; Løchen, Maja-Lisa; Mathiesen, Ellisiv B.; Nilsen, Amalie; Njølstad, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
      Aims - To investigate European guideline treatment target achievement in cardiovascular risk factors, medication use, and lifestyle, after myocardial infarction (MI) or ischaemic stroke, in women and men living in Norway.<p> <p>Methods and results - In the population-based Tromsø Study 2015–16 (attendance 65%), 904 participants had previous validated MI and/or stroke. Cross-sectionally, we ...
    • Trends in prevalence, treatment and control of hypertension in 38,825 adults over 36 years in Tromsø prospective study 

      Desai, Trishna; Clarke, Robert; Ross, Stephanie; Grimsgaard, Sameline; Njølstad, Inger; Lewington, Sarah (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-25)
      Aims/Background: Serial blood pressure surveys in cohort studies can inform public health policies to control blood pressure for prevention of cardiovascular diseases.<p> <p>Methods: Mean levels of systolic blood pressure (SBP) were collected in six sequential surveys, involving 38,825 individuals aged 30–79 years (51% female), between 1979 and 2015 in the Tromsø Study in Norway. Mean levels of ...
    • Using cloud-based physical activity data from Google Fit and Apple HealthKit to expand recording of physical activity data in a population study 

      Henriksen, André; Hopstock, Laila Arnesdatter; Hartvigsen, Gunnar; Grimsgaard, Sameline (Journal article; Tidsskriftartikkel, 2017)
      Large population studies are important sources for medical research. These studies are well planned, well organized, and costly. However, people record health data themselves using different sensors, which are mostly unplanned, unorganized and inexpensive. Nevertheless, self-recorded data might be an important supplement to population studies. The question is how to access and use this data. In the ...