Blar i forfatter "Dossus, Laure"

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    • An epidemiologic risk prediction model for ovarian cancer in Europe: The EPIC study 

      Li, Kuanrong; Hüsing, Anika; Fortner, Renée Turzanski; Tjønneland, Anne; Hansen, Louise Seier; Dossus, Laure; Chang-Claude, Jenny; Bergmann, Manuela M.; Steffen, Annika; Bamia, Christina; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Palli, Domenico; Mattiello, Amalia; Agnoli, Claudia; Tumino, Rosaria; Onland-Moret, N. Charlotte; Peeters, Petra H.; Bueno-de-Mesquita, H. Bas; Gram, Inger Torhild; Weiderpass, Elisabete; Sánchez-Cantalejo, Emilio; Chirlaque, María-Dolores; Duell, Eric J.; Ardanaz, Eva; Idahl, Annika; Lundin, Eva; Khaw, Kay-Tee; Travis, Ruth C.; Merritt, Melissa A.; Gunter, Marc J.; Riboli, Elio; Ferrari, Pietro; Terry, Kathryn L.; Cramer, Daniel William; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-05)
      Background: Ovarian cancer has a high case-fatality ratio, largely due to late diagnosis. Epidemiologic risk prediction models could help identify women at increased risk who may benefit from targeted prevention measures, such as screening or chemopreventive agents.<p> <p>Methods: We built an ovarian cancer risk prediction model with epidemiologic risk factors from 202 206 women in the European ...

    • Exogenous hormone use and cutaneous melanoma risk in women: The European Prospective Investigation into Cancer and Nutrition 

      Cervenka, Iris; Al Rahmoun, Marie; Mahamat-Saleh, Yahya; Fournier, Agnès; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Caini, Saverio; Palli, Domenico; Ghiasvand, Reza; Veierød, Marit Bragelien; Botteri, Edoardo; Tjønneland, Anne; Olsen, Anja; Fortner, Renée T.; Kaaks, Rudolf; Schulze, Matthias B.; Panico, Salvatore; Trichopoulou, Antonia; Dessinioti, Clio; Niforou, Katerina; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Hendrik Bastiaan; Sandanger, Torkjel M; Colorado-Yohar, Sandra; Sánchez, María-José; Gil Majuelo, Leire; Lujan-Barroso, Leila; Ardanaz, Eva; Merino, Susana; Isaksson, Karolin; Butt, Salma; Ljuslinder, Ingrid; Jansson, Malin; Travis, Ruth C.; Khaw, Kay-Tee; Weiderpass, Elisabete; Dossus, Laure; Rinaldi, Sabina; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      Evidence suggests an influence of sex hormones on cutaneous melanoma risk, but epidemiologic findings are conflicting. We examined the associations between use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk in women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a prospective cohort study initiated in 1992 in 10 ...

    • Fiber intake modulates the association of alcohol intake with breast cancer 

      Romieu, Isabelle; Ferrari, Pietro; Chajès, Véronique; de Batlle, Jordi; Biessy, Carine; Scoccianti, Chiara; Dossus, Laure; Boutron, Marie Christine; Bastide, Nadia; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; Quirós, J Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano Etxezarreta, Pilar; Borgquist, Signe; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-06)
      Alcohol intake has been related to an increased risk of breast cancer (BC) while dietary fiber intake has been inversely associated to BC risk. A beneficial effect of fibers on ethanol carcinogenesis through their impact on estrogen levels is still controversial. We investigated the role of dietary fiber as a modifying factor of the association of alcohol and BC using data from the European Prospective ...

    • Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort 

      Engeset, Dagrun; Braaten, Tonje; Teucher, Birgit; Kuhn, Tilman; Bueno-de-Mesquita, HB; Leenders, Max; Agudo, Antonio; Bergmann, Manuela M; Valanou, Elisavet; Naska, Androniki; Trichopoulou, Antonia; Key, Timothy J; Crowe, Francesca L; Overvad, Kim; Sonestedt, Emily; Mattiello, Amalia; Peeters, Petra H; Wennberg, Maria; Jansson, Jan Håkan; Boutron-Ruault, Marie-Christine; Dossus, Laure; Dartois, Laureen; Li, Kuanrong; Barricarte, Aurelio; Ward, Heather; Riboli, Elio; Agnoli, Claudia; Huerta, Jose Maria; Sanchez, Maria-Jose; Tumino, Rosario; Altzibar, Jone M; Vineis, Paolo; Masala, Giovanna; Ferrari, Pietro; Muller, David C; Johansson, Mattias; Luisa Redondo, M; Tjønneland, A; Olsen, Anja; Olsen, Karina Standahl; Brustad, Magritt; Skeie, Guri; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3) 

      Canzian, Federico; Lund, Eiliv; Kaaks, Rudolf; Cox, David G.; Henderson, Katherine D.; Henderson, Brian E.; Berg, Christine; Bingham, Sheila; Boeing, Heiner; Buring, Julie; Calle, Eugenia E.; Chanock, Stephen; Clavel-Chapelon, Francoise; Dossus, Laure; Feigelson, Heather Spencer; Haiman, Christopher A.; Hankinson, Susan E.; Hoover, Robert; Hunter, David J.; Isaacs, Claudine; Lenner, Per; Overvad, Kim; Palli, Domenico; Pearce, Celeste Leigh; Quiros, Jose R.; Riboli, Elio; Stram, Daniel O.; Thomas, Gilles; Thun, Michael J.; Trichopoulos, Dimitrios; van Gils, Carla H.; Ziegler, Regina G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-07-29)
      Background: Gonadotropin releasing hormone (GNRH1) triggers the release of follicle stimulating hormone and luteinizing hormone from the pituitary. Genetic variants in the gene encoding GNRH1 or its receptor may influence breast cancer risk by modulating production of ovarian steroid hormones. We studied the association between breast cancer risk and polymorphisms in genes that code for GNRH1 ...

    • Genetic risk variants associated with in situ breast cancer 

      Campa, Daniele; Barrdahl, Myrto; Gaudet, Mia M.; Black, Amanda; Chanock, Stephen J.; Diver, W. Stephen; Gapstur, Susan M.; Haiman, Christopher; Hankinson, Susan; Hazra, Aditi; Henderson, Brian; Hoover, Robert N.; Hunter, David J.; Joshi, Amit; Kraft, Peter; Le Marchand, Loic; Lindström, Sara; Willett, Walter; Travis, Ruth C.; Amiano, Pilar; Siddiq, Afshan; Trichopoulos, Dimitrios; Sund, Malin; Tjønneland, Anne; Weiderpass, Elisabete; Peeters, Petra H.; Panico, Salvatore; Dossus, Laure; Ziegler, Regina G.; Canzian, Federico; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-13)
      Introduction: Breast cancer in situ (BCIS) diagnoses, a precursor lesion for invasive breast cancer, comprise about 20 % of all breast cancers (BC) in countries with screening programs. Family history of BC is considered one of the strongest risk factors for BCIS.<p><p>Methods: To evaluate the association of BC susceptibility loci with BCIS risk, we genotyped 39 single nucleotide polymorphisms (SNPs), ...

    • Healthy lifestyle and risk of cancer in the European prospective investigation into cancer and nutrition cohort study 

      McKenzie, Fiona; Biessy, Carine; Ferrari, Pietro; Freisling, Heinz; Rinaldi, Sabina; Chajes, Veronique; Dahm, Christina C; Overvad, Kim; Dossus, Laure; Lagiou, Pagona; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Bas Bueno-De-Mesquita, H; May, Anne; Peeters, Petra H; Weiderpass, Elisabete; Sanchez, Maria-Jose; Navarro, Carmen; Ardanaz, Eva; Ericson, Ulrica; Wirfalt, Elisabet; Travis, Ruth C; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04)
      It has been estimated that at least a third of the most common cancers are related to lifestyle and as such are preventable. Key modifiable lifestyle factors have been individually associated with cancer risk; however, less is known about the combined effects of these factors. This study generated a healthy lifestyle index score (HLIS) to investigate the joint effect of modifiable factors on ...

    • High levels of C-reactive protein are associated with an increased risk of ovarian cancer: Results from the Ovarian Cancer Cohort Consortium 

      Peres, Lauren C.; Mallen, Adrianne R.; Townsend, Mary K.; Poole, Elizabeth M.; Trabert, Britton; Allen, Naomi E.; Arslan, Alan A.; Dossus, Laure; Fortner, Renee T.; Gram, Inger T.; Hartge, Patricia; Idahl, Annika; Kaaks, Rudolf; Kvaskoff, Marina; Magliocco, Anthony M.; Merritt, Melissa A.; Quirós, Ramón; Tjonneland, Anne; Trichopoulou, Antonia; Tumino, Rosario; van Gils, Carla H.; Visvanathan, Kala; Wentzensen, Nicolas; Zeleniuch-Jacquotte, Anne; Tworoger, Shelley S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-28)
      Growing epidemiologic evidence supports chronic inflammation as a mechanism of ovarian carcinogenesis. An association between a circulating marker of inflammation, C-reactive protein (CRP), and ovarian cancer risk has been consistently observed, yet, potential heterogeneity of this association by tumor and patient characteristics has not been adequately explored. In this study, we pooled data from ...

    • Inflammatory potential of the diet and association with risk of differentiated thyroid cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Dossus, Laure; Shivappa, Nitin; Hébert, James R.; Agudo, Antonio; Tjonneland, Anne; Halkjaer, Jytte; Overvad, Kim; Katzke, Verena A.; Le Cornet, Charlotte; Schulze, Matthias B.; Jannasch, Franziska; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Dragna, Luca; Iannuzzo, Gabriella; Jensen, Torill Miriam Enget; Brustad, Magritt; Skeie, Guri; Zamora-Ros, Raul; Rodriguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, María-Dolores; Ardanaz, Eva; Almquist, Martin; Sonestedt, Emily; Sandström, Maria; Nilsson, Lena Maria; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina; Boutron-Ruault, Marie-Christine; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-30)
      Purpose - Chronic inflammation is thought to initiate or promote differentiated thyroid cancer (DTC) and previous studies have shown that diet can modulate this inflammatory process. We aimed to evaluate the association of several dietary scores reflecting the inflammatory potential of the diet with DTC risk.<p> <p>Methods - Within the EPIC cohort, 450,063 participants were followed during a mean ...

    • Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohort 

      Ose, Jennifer; Fortner, Renée T; Schock, Helena; Peeters, Petra H.; Onland-Moret, N. Charlotte; Bueno-de-Mesquita, H. Bas; Weiderpass, Elisabete; Gram, Inger Torhild; Overvad, Kim; Tjønneland, Anne; Dossus, Laure; Fournier, Agnes; Baglietto, Laura; Trichopoulou, Antonia; Benetou, Vassiliki; Trichopoulos, Dimitrios; Boeing, Heiner; Masala, Giovanna; Krogh, Vittorio; Matiello, Amalia; Tumino, Rosaria; Popovic, Maja; Obón-Santacana, Mireia; Larrañaga, Nerea; Ardanaz, Eva; Sánchez, María-José; Menéndez, Virginia; Chirlaque, María-Dolores; Travis, Ruth C.; Khaw, Kay-Tee; Brändstedt, Jenny; Idahl, Annika; Lundin, Eva; Rinaldi, Sabina; Kuhn, Elisabetta; Romieu, Isabelle; Gunter, Marc J.; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-04)
      Background: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics ...

    • Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Schmidt, Julie A.; Travis, Ruth C.; Gunter, Marc; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Lécuyer, Lucie; Rothwell, Joseph A.; Severi, Gianluca; Johnson, Theron; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Macciotta, Alessandra; Boer, Jolanda M. A.; Monninkhof, Evelyn; Olsen, Karina Standahl; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Agudo, Antonio; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Ardanaz, Eva; Vidman, Linda; Winkvist, Anna; Heath, Alicia K.; Weiderpass, Elisabete; Huybrechts, Inge; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Background: Metabolomics is a promising molecular tool for identifying novel etiological pathways leading to cancer. In an earlier prospective study among pre- and postmenopausal women not using exogenous hormones, we observed a higher risk of breast cancer associated with higher blood concentrations of one metabolite (acetylcarnitine) and a lower risk associated with higher blood concentrations of ...

    • Lifetime alcohol use and overall and cause-specific mortality in the European Prospective Investigation into Cancer and nutrition (EPIC) study 

      Ferrari, Pietro; Licaj, Idlir; Muller, David C; Andersen, Per Kragh; Johansson, Mattias; Boeing, Heiner; Weiderpass, Elisabete; Dossus, Laure; Dartois, Laureen; Fagherazzi, Guy; Bradbury, Kathryn E; Khaw, Kay-Tee; Wareham, Nick; Duell, Eric J; Barricarte, Aurelio; Molina-Montes, Esther; Sanchez, Carmen Navarro; Arriola, Larraitz; Wallström, Peter; Tjønneland, Anne; Olsen, Anja; Trichopoulou, Antonia; Benetou, Vasiliki; Trichopoulos, Dimitrios; Tumino, Rosario; Agnoli, Claudia; Sacerdote, Carlotta; Palli, Domenico; Li, Kuanrong; Kaaks, Rudolf; Peeters, Petra; Beulens, Joline WJ; Nunes, Luciana; Gunter, Marc; Norat, Teresa; Overvad, Kim; Brennan, Paul; Riboli, Elio; Romieu, Isabelle (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Long-term weight change and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Ellingjord-Dale, Merete; Christakoudi, Sofia; Weiderpass, Elisabete; Panico, Salvatore; Dossus, Laure; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Gram, Inger Torhild; Skeie, Guri; Rosendahl, Ann H.; Sund, Malin; Key, Tim; Ferrari, Pietro; Gunter, Marc; Heath, Alicia K; Tsilidis, Konstantinos K; Riboli, Eilo; Sánchez, Maria-Jose; Lopez, Maria-Dolores Chirlaque; Peppa, Eleni; Trichopoulou, Antonia; Martimianaki, Georgia; Agudo, Antonio; Santiuste, Carmen; Ardanaz, Eva; Amiano, Pilar; Boutron-Ruault, Marie-Chiristine; Simeon, Vittorio; Berrino, Franco; Tumino, Rosario; Severi, Gianluca; Stocks, Tanja; Turzanski-Fortner, Renée; Rylander, Charlotta; Aune, Dagfinn; Dahm, Christina Catherine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
      Background: The role of obesity and weight change in breast-cancer development is complex and incompletely understood. We investigated long-term weight change and breast-cancer risk by body mass index (BMI) at age 20 years, menopausal status, hormone replacement therapy (HRT) and hormone-receptor status.<p><p> Methods: Using data on weight collected at three different time points from women ...

    • Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition 

      Kliemann, Nathalie; Viallon, Vivian; Murphy, Neil; Beeken, Rebecca J.; Rothwell, Joseph A.; Rinaldi, Sabina; Assi, Nada; van Roekel, Eline H.; Schmidt, Julie A.; Borch, Kristin Benjaminsen; Agnoli, Claudia; Rosendahl, Ann H.; Sartor, Hanna; Huerta, José María; Tjønneland, Anne; Halkjær, Jytte; Bueno-de-Mesquita, Bas; Gicquiau, Audrey; Achaintre, David; Aleksandrova, Krasimira; Schulze, Matthias B.; Heath, Alicia K.; Tsilidis, Konstantinos K.; Masala, Giovanna; Panico, Salvatore; Kaaks, Rudolf; Fortner, Renée T.; Van Guelpen, Bethany; Dossus, Laure; Scalbert, Augustin; Keun, Hector C.; Travis, Ruth C.; Jenab, Mazda; Johansson, Mattias; Ferrari, Pietro; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-30)
      Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study.<p> <p>Methods: Targeted mass spectrometry ...

    • Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Kliemann, Nathalie; Ammar, Romain Ould; Biessy, Carine; Gicquiau, Audrey; Katzke, Verena; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Sánchez, Maria-Jose; Crous-Bou, Marta; Pasanisi, Fabrizio; Tin, Sandar Tin; Perez-Cornago, Aurora; Aune, Dagfinn; Christakoudi, Sofia; Heath, Alicia K.; Colorado-Yohar, Sandra M.; Grioni, Sara; Skeie, Guri; Sartor, Hanna; Idahl, Annika; Rylander, Charlotta; May, Anne M.; Weiderpass, Elisabete; Freisling, Heinz; Playdon, Mary C.; Rinaldi, Sabina; Murphy, Neil; Huybrechts, Inge; Dossus, Laure; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-01)
      Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known.<p> <p>Methods: The association of metabolically defined body size phenotypes with endometrial cancer risk was investigated in a nested case–control study (817 cases/ 817 controls) within the European Prospective Investigation ...

    • Mitochondrial DNA copy number variation, leukocyte telomere length, and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Campa, Daniele; Barrdahl, Myrto; Santoro, Aurelia; Severi, Gianluca; Baglietto, Laura; Omichessan, Hanane; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Weiderpass, Elisabete; Chirlaque, Maria-Dolores; Rodríguez-Barranco, Miguel; Agudo, Antonio; Gunter, Marc; Dossus, Laure; Krogh, Vittorio; Matullo, Giuseppe; Trichopoulou, Antonia; Travis, Ruth C.; Canzian, Federico; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-17)
      <p><i>Background</i>: Leukocyte telomere length (LTL) and mitochondrial genome (mtDNA) copy number and deletions have been proposed as risk markers for various cancer types, including breast cancer (BC).</p> <p><i>Methods</i>: To gain a more comprehensive picture on how these markers can modulate BC risk, alone or in conjunction, we performed simultaneous measurements of LTL and mtDNA copy number ...

    • A Nested Case–Control Study of Metabolically Defined Body Size Phenotypes and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Cross, Amanda J; Abubakar, Mustapha; Jenab, Mazda; Aleksandrova, Krasmira; Boutron-Ruault, Marie-Christine; Dossus, Laure; Racine, Antoine; Kühn, Tilman; Katzke, Verena A.; Tjønneland, Anne; Petersen, Kristina E N; Overvad, Kim; Quiros, J Ramon; Jakszyn, Paula; Molina-Montes, Esther; Dorronsoro, Miren; Huerta, José-Maria; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nick; Travis, Ruth C; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Siersema, Peter D; Peeters, Petra H; Ohlsson, Bodil; Ericson, Ulrika; Palmqvist, Richard; Nyström, Hanna; Weiderpass, Elisabete; Skeie, Guri; Freisling, Heinz; Kong, So Yeon; Tsilidis, Kostas; Muller, David C; Riboli, Eilo; Gunter, Marc J (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-05)
      Background:<br> Obesity is positively associated with colorectal cancer. Recently, body size subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and metabolically healthy overweight/obese individuals (without hyperinsulinaemia) have been suggested to be at lower risk of cardiovascular disease than their metabolically unhealthy (hyperinsulinaemic) overweight/obese counterparts. ...

    • A new pipeline for the normalization and pooling of metabolomics data 

      Viallon, Vivian; His, Mathilde; Rinaldi, Sabina; Breeur, Marie; Gicquiau, Audrey; Hémon, Bertrand; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha Linn; Rothwell, Joseph A.; Lecuyer, Lucie; Severi, Gianluca; Kaaks, Rudolf; Johnson, Theron; Schulze, Matthias B.; Palli, Domenico; Agnoli, Claudia; Panico, Salvatore; Tumino, Rosaria; Ricceri, Fulvio; Monique Verschuren, Verschuren; Engelfriet, Peter; Onland-Moret, Charlotte; Vermeulen, Roel; Nøst, Therese Haugdahl; Urbarova, Ilona; Zamora-Ros, Raul; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Melander, Olle; Ottoson, Filip; Vidman, Linda; Rentoft, Matilda; Schmidt, Julie A.; Travis, Ruth C.; Weiderpass, Elisabete; Johansson, Mattias; Dossus, Laure; Jenab, Mazda; Gunter, Marc; Bermejo, Justo Lorenzo; Scherer, Dominique; Salek, Reza M.; Keski-Rahkonen, Pekka; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-17)

    • Osteoprotegerin and breast cancer risk by hormone receptor subtype: A nested case-control study in the EPIC cohort 

      Fortner, Renée T.; Sarink, Danja; Schock, Helena; Johnson, Theron; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Affret, Aurelie; His, Mathilde; Boutron-Ruault, Marie-Christine; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Palli, Domenico; Sieri, Sabina; Mattiello, Amalia; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.M.; van Gils, Carla H.; Weiderpass, Elisabete; Lund, Eiliv; Quirós, J. Ramón; Agudo, Antonio; Sánchez, María-José; Chirlaque, María-Dolores; Ardanaz, Eva; Dorronsoro, Miren; Key, Tim; Khaw, Kay-Tee; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A.; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-08)
      Background:<br>Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role as the decoy receptor for both the RANK ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Circulating OPG and breast cancer risk has been examined in only one prior study.<br>Methods:<br>A case-control ...

    • Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition 

      Breeur, Marie; Ferrari, Pietro; Dossus, Laure; Jenab, Mazda; Johansson, Mattias; Rinaldi, Sabina; Travis, Ruth C.; His, Mathilde; Key, Tim J.; Schmidt, Julie A.; Overvad, Kim; Tjønneland, Anne; Kyrø, Cecilie; Rothwell, Joseph A.; Laouali, Nasser; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Eichelmann, Fabian; Palli, Domenico; Grioni, Sara; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Bas; Olsen, Karina Standahl; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Quirós, J. Ramón; Bonet, Catalina; Barranco, Miguel Rodríguez; Chirlaque, María-Dolores; Ardanaz, Eva; Sandsveden, Malte; Manjer, Jonas; Vidman, Linda; Rentoft, Matilda; Muller, David; Tsilidis, Kostas; Heath, Alicia K.; Keun, Hector; Adamski, Jerzy; Keski-Rahkonen, Pekka; Scalbert, Augustin; Gunter, Marc J.; Viallon, Vivian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-19)
      Background - Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific cancer types separately. Here, we designed a multivariate pan-cancer analysis to identify metabolites potentially associated with multiple cancer types, while also allowing the investigation of cancer type-specific associations.<p> <p>Methods - We analysed targeted metabolomics ...