Blar i forfatter "Besada, Emilio"
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Risk Factors and Adverse Events Poorly Predict Infections and Hypogammaglobulinemia in Granulomatosis with Polyangiitis Patients Receiving Rituximab
Besada, Emilio (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)Background. 29 GPA patients from the Northern Norway vasculitis disease registry received rituximab (RTX) induction and maintenance. 24% and 31% had, respectively, severe and chronic infections while 45% had hypogammaglobulinemia and 28% discontinued RTX due to hypogammaglobulinemia. The aim of the study was to examine how known predictors and adverse events interacted with adverse events using ... -
Rituximab-induced hypogammaglobulinemia and intravenous immunoglobulin replacement therapy do not protect against relapse in granulomatous with polyangiitis
Besada, Emilio (Journal article; Tidsskriftartikkel, 2016-08-10) -
Serum immunoglobulin levels and risk factors for hypogammaglobulinaemia during long-term maintenance therapy with rituximab in patients with granulomatosis with polyangiitis
Besada, Emilio; Koldingsnes, Wenche; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-05-15) -
Should Pneumocystis jiroveci prophylaxis be recommended with Rituximab treatment in ANCA-associated vasculitis?
Besada, Emilio; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Reports in haematology, transplantation medicine and rheumatology indicate that Rituximab, a B cell depleting therapy, increases the risk for Pneumocystis jiroveci pneumopathy. Patients with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis have an increased incidence of P. jiroveci pneumopathy compared to other autoimmune diseases and Rituximab is often used to induce and maintain ... -
Should rheumatoid factor in rheumatoid arthritis be sent to Davy Jones's Locker?
Besada, Emilio; Nikolaisen, Cathrin; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)This article reviews the characteristics and weaknesses of the rheumatoid factor (RF) assay compared with anticitrullinated peptide antibody (ACPA) testing in the work-up of patients with synovitis. This should lead physicians to change their ordering habits and replace RF by ACPA. For RA diagnosis, good clinical judgement based on clinical history, physical examination and routine laboratory work ... -
Staphylococcus Aureus carriage and long-term Rituximab treatment for Granulomatosis with polyangiitis
Besada, Emilio; Koldingsnes, Wenche; Nossent, Hans C (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-25)Objective. Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell depletion and hypogammaglobulinemia that occur during RTX treatment increase the risk of chronic SA nasal carriage and subsequent ... -
Staphylococcus Aureus carriage and long-term Rituximab treatment for Granulomatosis with polyangiitis
Besada, Emilio; Koldingsnes, Wenche; Nossent, Hans (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-25)Objective. Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell depletion and hypogammaglobulinemia that occur during RTX treatment increase the risk of chronic SA nasal carriage and subsequent ...