Blar i forfatter "Aleksandrova, Krasimira"

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    • Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study 

      Fortuin-de Smidt, Melony C.; Sewe, Maquins Odhiambo; Lassale, Camille; Weiderpass, Elisabete; Andersson, Jonas; Huerta, José María; Ekelund, Ulf; Aleksandrova, Krasimira; Tong, Tammy Yn; Dahm, Christina C.; Tjønneland, Anne; Kyrø, Cecilie; Steindorf, Karen; Schulze, Matthias B.; Katzke, Verena; Sacerdote, Carlotta; Agnoli, Claudia; Masala, Giovanna; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda Ma; Onland-Moret, N Charlotte; Wendel-Vos, Gc Wanda; van der Schouw, Yvonne T.; Borch, Kristin Benjaminsen; Agudo, Antonio; Petrova, Dafina; Chirlaque, María Dolores; Conchi, Moreno Iribas; Amiano, Pilar; Melander, Olle; Heath, Alicia K.; Aune, Dagfinn; Forouhi, Nita G.; Langenberg, Claudia; Brage, Soren; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam S.; Wennberg, Patrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-11)

    • Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study 

      Aglago, Elom K.; Schalkwijk, Casper G.; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Katzke, Verena; Johnson, Theron; Schulze, Matthias B.; Aleksandrova, Krasimira; Masala, Giovanna; Sieri, Sabina; Simeon, Vittorio; Tumino, Rosario; Macciotta, Alessandra; Bueno-De-Mesquita, Bas; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Jakszyn, Paula; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Perez-Cornago, Aurora; Mayén, Ana-Lucia; Weiderpass, Elisabete; Gunter, Marc J.; Heath, Alicia K.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
      Advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed by the non-enzymatic reaction between amino acids and reducing sugars, or dicarbonyls as intermediate compounds. Experimental studies suggest that AGEs may promote colorectal cancer, but prospective epidemiologic studies are inconclusive. We conducted a case–control study nested within a large European cohort. Plasma ...

    • Plasma polyphenols associated with lower high-sensitivity C-reactive protein concentrations: A cross-sectional study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Harms, Laura; Scalbert, Augustin; Zamora-Ros, Raul; Rinaldi, Sabina; Jenab, Mazda; Murphy, Neil; Achaintre, David; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Romana, Mancini; Mahamat-Saleh, Yahya; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katzke, Verena; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Panico, Salvatore; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, Hendrik Bastian; Vermeulen, Roel; Weiderpass, Elisabete; Nøst, Therese Haugdahl; Lasheras, Cristina; RodrÍguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Dorronsoro, Miren; Hultdin, Johan; Schmidt, Julie A.; Gunter, Marc; Riboli, Elio; Aleksandrova, Krasimira (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-04)
      Experimental studies have reported on the anti-inflammatory properties of polyphenols. However, results from epidemiological investigations have been inconsistent and especially studies using biomarkers for assessment of polyphenol intake have been scant. We aimed to characterise the association between plasma concentrations of thirty-five polyphenol compounds and low-grade systemic inflammation ...

    • Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations 

      Nimptsch, Katharina; Aleksandrova, Krasimira; Fedirko, Veronika; Jenab, Mazda; Gunter, Marc J.; Siersema, Peter D.; Wu, Kana; Katzke, Verena; Kaaks, Rudolf; Panico, Salvatore; Palli, Domenico; May, Anne M; Sieri, Sabina; Bueno-de-Mesquita, Bas; Olsen, Karina Standahl; Sánchez, Maria-Jose; Perez-Cornago, Aurora; Olsen, Anja; Tjønneland, Anne; Bonet, Catalina Bonet; Dahm, Christina C.; Chirlaque, María-Dolores; Fiano, Valentina; Tumino, Rosario; Gurrea, Aurelio Barricarte; Boutron-Ruault, Marie-Christine; Menegaux, Florence; Severi, Gianluca; van Guelpen, Bethany; Lee, Young-Ae; Pischon, Tobias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-24)
      <b><p>Background</b> The role of elevated pre-diagnostic C-reactive protein (CRP) concentrations on mortality in individuals with colorectal cancer (CRC) remains unclear. <b><p>Methods</b> We investigated the association between pre-diagnostic high-sensitivity CRP concentrations and CRP genetic variation associated with circulating CRP and CRC-specific and all-cause mortality based on ...

    • Reproductive factors and epithelial ovarian cancer survival in the EPIC cohort study 

      Bešević, Jelena; Gunter, Marc J; Fortner, Renée T.; Tsilidis, Konstantinos K; Weiderpass, Elisabete; Onland-Moret, N. Charlotte; Dossus, Laure; Tjønneland, Anne; Hansen, Louise; Overvad, Kim; Mesrine, Sylvie; Baglietto, Laura; Clavel-Chapelon, Françoise; Kaaks, Rudolf; Aleksandrova, Krasimira; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Bamia, Christina; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Jareid, Mie; Quirós, J. Ramón; Duell, Eric J; Sánchez, María-José; Larrañaga, Nerea; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Dias, Joana A.; Sonestedt, Emily; Idahl, Annika; Lundin, Eva; Wareham, Nicholas J.; Khaw, Kay-Tee; Travis, Ruth C.; Rinaldi, Sabina; Romieu, Isabelle; Riboli, Elio; Merritt, Melissa A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-10)
      Background: Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025 invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included 521 330 total ...

    • Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study. 

      Ritte, Rebecca; Tikk, Kaja; Lukanova, Annekatrin; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Dossus, Laure; Fournier, Agnes; Clavel-Chapelon, Françoise; Grote, Verena; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Berrino, Franco; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Quirós, José Ramón; Buckland, Genevieve; Molina-Montes, Esther; Chirlaque, María Dolores; Ardanaz, Eva; Amiano, Pilar; Bueno-de-Mesquita, H. Bas; van Gils, Carla H.; Peeters, Petra H M; Wareham, Nick; Khaw, Kay-Tee; Key, Timothy J; Travis, Ruth C.; Weiderpass, Elisabete; Dumeaux, Vanessa; Lund, Eiliv; Sund, Malin; Andersson, Anne; Romieu, Isabelle; Rinaldi, Sabina; Vineis, Paolo; Merritt, Melissa A; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain. Methods Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships of reproductive factors (menarcheal age, time between menarche and first pregnancy, parity, number of children, age at first and last pregnancies, time since last full-term ...